Tarrier Nicholas, Barrowclough Christine, Andrews Bernice, Gregg Lynsey
Academic Division of Clinical Psychology, Education and Research Building (2nd Floor), Wythenshawe Hospital, Manchester M23 9LT, UK.
Soc Psychiatry Psychiatr Epidemiol. 2004 Nov;39(11):927-37. doi: 10.1007/s00127-004-0828-3.
Suicide rates amongst schizophrenic patients are high. There are disadvantages in investigating successfully completed suicides which make suicidal ideation and previous attempts important proxy measures of suicidal risk. The aim of this study was to investigate factors associated with these risk measures.
Fifty-nine patients suffering recent onset schizophrenia were assessed for suicidal ideation and history, and a range of demographic, clinical, social (including relatives' Expressed Emotion) and self-esteem measures. Univariate comparisons were made between those with and without suicide ideation and previous attempts. Path analysis was conducted to identify factors directly or indirectly associated with a composite scale of risk (low, medium or high).
Approximately 25% of the sample reported a current desire to kill themselves and 47% had made one or more previous attempts. There were numerous significant univariate differences between those with or without ideation or history. Path analysis indicated that greater hopelessness (OR 1.22) and longer duration of illness (OR 1.13) increased risk. Hopelessness was associated with higher negative self-evaluation and social isolation. Negative self-evaluation was associated with more relatives' criticism which was associated with more negative symptoms. Being a male, unmarried and unemployed were all significantly associated with an increase in negative symptoms. Social isolation was associated with being unemployed, older, more positive symptoms and longer illness duration. Duration of illness was not itself predicted by any other variables.
Non-fatal suicide ideation and behaviour are significantly associated with an array of demographic, clinical, interpersonal and psychological factors. To reduce risk of suicide, these factors need to be assessed and methods developed to reduce their influence.
精神分裂症患者的自杀率很高。调查成功完成的自杀存在弊端,这使得自杀意念和既往自杀未遂成为自杀风险的重要替代指标。本研究的目的是调查与这些风险指标相关的因素。
对59例近期发病的精神分裂症患者进行自杀意念和病史评估,以及一系列人口统计学、临床、社会(包括亲属的情感表达)和自尊测量。对有自杀意念和既往自杀未遂者与无自杀意念和既往自杀未遂者进行单因素比较。进行路径分析以确定与综合风险量表(低、中或高)直接或间接相关的因素。
约25%的样本报告目前有自杀意愿,47%有过一次或多次既往自杀未遂。有自杀意念或病史者与无自杀意念或病史者之间存在许多显著的单因素差异。路径分析表明,更大的绝望感(比值比1.22)和更长的病程(比值比1.13)会增加风险。绝望感与更高的负面自我评价和社会隔离有关。负面自我评价与更多亲属的批评有关,而亲属的批评又与更多的阴性症状有关。男性、未婚和失业均与阴性症状增加显著相关。社会隔离与失业、年龄较大、更多的阳性症状和更长的病程有关。病程本身不受任何其他变量的预测。
非致命性自杀意念和行为与一系列人口统计学、临床、人际和心理因素显著相关。为降低自杀风险,需要对这些因素进行评估,并开发方法以减少其影响。