Nishida Masato, Tsunoda Hajime, Ichikawa Yoshihito, Yoshikawa Hiroyuki
Kasumigaura National Hospital, 2-7-14 Shimotakatsu, Tsuchiura 300-8585, Japan.
Int J Clin Oncol. 2004 Oct;9(5):403-5. doi: 10.1007/s10147-004-0413-5.
A 55-year-old multiparous woman was diagnosed with stage IIIc ovarian clear cell carcinoma. Three years after the first surgery and adjuvant chemotherapy with irinotecan hydrochloride and mitomycin C, she developed common iliac lymph node recurrence. Two cycles of chemotherapy with irinotecan hydrochloride and nedaplatin led to a complete response. Surgical resection revealed pathological complete response. The chemosensitivity of ovarian clear cell carcinoma has been reported to be very poor. No standard chemotherapeutic regimens for this carcinoma have been established. The present study is the first report of a pathological complete response in a patient with advanced ovarian clear cell carcinoma. Future studies are needed to confirm the efficacy of this regimen for this carcinoma.
一名55岁的经产妇被诊断为IIIc期卵巢透明细胞癌。在首次手术及接受盐酸伊立替康和丝裂霉素C辅助化疗三年后，她出现了髂总淋巴结复发。两周期的盐酸伊立替康和奈达铂化疗导致完全缓解。手术切除显示病理完全缓解。据报道，卵巢透明细胞癌的化疗敏感性非常差。尚未确立针对该癌症的标准化疗方案。本研究是晚期卵巢透明细胞癌患者出现病理完全缓解的首例报告。需要进一步的研究来证实该方案对这种癌症的疗效。
