Kleemann D, Nofz S, Plank I, Schlottmann A
MediClin AG, HNO-Klinik der Müritz-Klinikum GmbH Waren, Waren.
HNO. 2005 Apr;53(4):333-6. doi: 10.1007/s00106-004-1108-y.
The healing process after functional endoscopic sinus surgery (FESS) normally takes weeks to months under an intensive therapy regime. Occasionally, symptomatic failures and local problems occur despite extensive follow-up treatment.
Over a 3-year period 900 patients underwent FESS in our department. Of these patients, 79 were found with no tendency toward improvement of symptoms and signs more than 3 weeks after the operation. Nasal obstruction, frontal headache, and postnasal drainage were evaluated to be the frequent postoperative complaints. Scarring of the middle meatal antrotomy and the ethmoid, inflammatory granulation, and early recurrence of polyps occurred as the local problems. Historical factors and clinical signs of gastroesophageal or laryngopharyngeal reflux were examined in this group. Afterwards, proton pump inhibitors were prescribed on a trial basis.
Historical clues of reflux were reported by 30 patients only. However, clinical signs of a reflux were found in 66 cases. Rhinological symptoms and signs were improved in 60 patients following the application of proton pump inhibitors over 2 weeks.
Our results support earlier experiences reported in the literature. Laryngopharyngeal reflux could be a factor altering the healing process after FESS.
在强化治疗方案下,功能性鼻内镜鼻窦手术(FESS)后的愈合过程通常需要数周至数月。尽管进行了广泛的后续治疗,但偶尔仍会出现症状性失败和局部问题。
在3年期间,我们科室有900例患者接受了FESS。在这些患者中,79例在术后3周以上症状和体征无改善趋势。鼻塞、前额头痛和鼻后滴漏被评估为常见的术后主诉。中鼻道鼻窦切开术和筛窦的瘢痕形成、炎性肉芽组织以及息肉的早期复发为局部问题。对该组患者检查了胃食管或喉咽反流的历史因素和临床体征。之后,试验性地开具质子泵抑制剂。
仅30例患者报告有反流的历史线索。然而,66例发现有反流的临床体征。在应用质子泵抑制剂2周后,60例患者的鼻科症状和体征得到改善。
我们的结果支持文献中早期报道的经验。喉咽反流可能是改变FESS后愈合过程的一个因素。