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戒烟为时已晚?一项纵向研究中吸烟与戒烟对老年人发病率和死亡率的影响。

Too late to quit? Effect of smoking and smoking cessation on morbidity and mortality among the elderly in a longitudinal study.

作者信息

Hsu Hui-Chuan, Pwu Raoh-Fang

机构信息

Department of Health Care Administration, Taichung Healthcare and Management University, Wufeng Shiang, Taichung, Taiwan.

出版信息

Kaohsiung J Med Sci. 2004 Oct;20(10):484-91. doi: 10.1016/S1607-551X(09)70247-5.

Abstract

This prospective study of the elderly population estimated the risks of smoking for morbidity and mortality and identified whether cessation of smoking reduced the risk of disease. Data came from face-to-face interviews that used a population-based probability sample of those aged 60 years or over in Taiwan, provided by the Population and Health Research Center, Bureau of Health Promotion. In total, 4,049 subjects were included at the baseline year of 1989 and followed up in 1993 and 1996. Smoking-related variables included current smoking status, smoking history, daily consumption, and years since the cessation of smoking. Cox regression models were used to analyze the relative risks for morbidity and mortality, controlling for demographics, physical function, and comorbidities. The sample was made up of 50.2% nonsmokers, 15.2% ex-smokers, and 34.6% current smokers in the baseline year. Current smokers were more likely to have lower respiratory tract diseases throughout the study. Current smokers had a higher risk of stroke from 1989 to 1993. No dose-response relationship for smoking exposure or impact of years since smoking cessation was found. Whether cessation of smoking is protective should be investigated for middle-aged adults followed to old age. An effective strategy for smoking cessation in the elderly is suggested, and people should be encouraged to quit smoking at any time.

摘要

这项针对老年人群的前瞻性研究估计了吸烟对发病和死亡的风险,并确定戒烟是否能降低疾病风险。数据来自面对面访谈,这些访谈采用了由台湾健康促进局人口与健康研究中心提供的基于人群概率抽样的60岁及以上人群样本。1989年基线年共纳入4049名受试者,并在1993年和1996年进行随访。与吸烟相关的变量包括当前吸烟状况、吸烟史、每日吸烟量以及戒烟年限。使用Cox回归模型分析发病和死亡的相对风险,并对人口统计学、身体功能和合并症进行控制。在基线年,样本由50.2%的非吸烟者、15.2%的已戒烟者和34.6%的当前吸烟者组成。在整个研究过程中,当前吸烟者更易患下呼吸道疾病。1989年至1993年期间,当前吸烟者患中风的风险更高。未发现吸烟暴露的剂量反应关系或戒烟年限的影响。对于从中年到老年的成年人,应研究戒烟是否具有保护作用。建议制定一项针对老年人的有效戒烟策略,并应鼓励人们随时戒烟。

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