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[阿仑膦酸钠的每周和每日摄入量:骨质疏松症治疗中耐受性的比较]

[Weekly and daily intake of alendronate: comparison of tolerance in osteoporosis treatment].

作者信息

Sakić Davorin, Badovinac Olga, Delija Alboran, Sakić Vjekoslava Amerl

机构信息

Odjel za fizikalnu medicinu i rehabilitaciju, Klinicka bolnica Dubrava, Avenija G. Suska 6, 10000 Zagreb.

出版信息

Reumatizam. 2004;51(1):23-5.

PMID:15554368
Abstract

In this study we analyzed, considering complains of patients, tolerance of taking alendronate 70 mg once a week in comparison with daily intake of alendronate 10 mg. Subjects were patients that were treated for osteoporosis at Department for physical medicine and rehabilitation in Clinical hospital Dubrava. The diagnosis of osteoporosis was established by DXA densitometry. Pains in oesophagus were the main reason for ceasing of use of alondronate. According to our research patients tolerate taking alendronate 70 weekly 4,22 times better than alendronate 10 daily.

摘要

在本研究中,我们根据患者的主诉,分析了每周服用一次70毫克阿仑膦酸盐与每日服用10毫克阿仑膦酸盐的耐受性。研究对象为在杜布拉瓦临床医院物理医学与康复科接受骨质疏松症治疗的患者。骨质疏松症的诊断通过双能X线吸收法骨密度测定确定。食管疼痛是停用阿仑膦酸盐的主要原因。根据我们的研究,患者每周服用70毫克阿仑膦酸盐的耐受性比每日服用10毫克阿仑膦酸盐好4.22倍。

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