Morrow Daniel G, Weiner Michael, Deer Melissa M, Young James M, Dunn Sarah, McGuire Patricia, Murray Michael D
Institute of Aviation, University of Illinois at Urbana-Champaign, Urbana-Champaign, Illinois, USA.
Am J Geriatr Pharmacother. 2004 Mar;2(1):44-52. doi: 10.1016/s1543-5946(04)90006-2.
Chronic heart failure (CHF) is associated with reduced functional capacity and quality of life, particularly among older adults. Complex medication regimens for CHF challenge older patients' ability to adhere to them, in part because of age-related cognitive decline and poor communication about medications.
This article describes patient-centered instructions for taking CHF medications that were developed as part of a multifaceted pharmacy-based intervention to improve medication adherence and health-related outcomes among older adults with CHF. The findings of 3 initial validation studies investigating patients' reactions to the instructions are reported.
Patients' responses to the instructions were measured using focus group (study 1) and questionnaire (studies 2 and 3) techniques.
Overall, older adults with CHF in the 3 studies preferred the patient-centered instructions to the standard pharmacy instructions (93.8% in study 1, 65.0% in study 2). In addition, participants' preferences depended on their medication-related goals. A preference for patient-centered instructions reflected a focus on ease of understanding (as supported by the use of large type size, icons, and patient-centered organization), whereas a preference for the standard pharmacy instructions reflected a focus on the amount of information provided about drug interactions (studies 2 and 3).
In the 3 validation studies, older adults with CHF tended to prefer the patient-centered instructions to the standard pharmacy instructions, although the results were not statistically significant in study 2. This suggests that the use of such instructions may improve patients' medication knowledge and their adherence to treatment regimens.
慢性心力衰竭(CHF)与功能能力和生活质量下降有关,在老年人中尤为明显。CHF的复杂药物治疗方案对老年患者坚持服药的能力构成挑战,部分原因是与年龄相关的认知能力下降以及药物沟通不畅。
本文描述了以患者为中心的CHF药物服用说明,这些说明是作为一项多方面的基于药房的干预措施的一部分而制定的,旨在提高老年CHF患者的药物依从性和与健康相关的结果。报告了3项初步验证研究调查患者对这些说明反应的结果。
使用焦点小组(研究1)和问卷调查(研究2和3)技术来衡量患者对这些说明的反应。
总体而言,3项研究中的老年CHF患者更喜欢以患者为中心的说明,而不是标准药房说明(研究1中为93.8%,研究2中为65.0%)。此外,参与者的偏好取决于他们与药物相关的目标。对以患者为中心的说明的偏好反映了对易于理解的关注(使用大号字体、图标和以患者为中心的组织方式可证明这一点),而对标准药房说明的偏好反映了对提供的药物相互作用信息数量的关注(研究2和3)。
在这3项验证研究中,老年CHF患者倾向于更喜欢以患者为中心的说明,而不是标准药房说明,尽管研究2的结果在统计学上不显著。这表明使用此类说明可能会提高患者的用药知识及其对治疗方案的依从性。