Tanaka Yumiko Oishi, Nishida Masato, Tsunoda Hajime, Okamoto Yoshikazu, Yoshikawa Hiroyuki
Department of Radiology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan.
J Magn Reson Imaging. 2004 Dec;20(6):998-1007. doi: 10.1002/jmri.20207.
To study the MR characteristics of nonbenign uterine smooth muscle tumors.
Nine patients with pathologically proven leiomyosarcomas, and three patients with smooth muscle tumors of uncertain malignant potential (SMTUMP) were included in this study. Twelve cases of benign uterine leiomyomas and variants, in which gynecologists suspected leiomyosarcomas, were also analyzed. In each case we studied the size, location, signal intensity, and contrast enhancement of the tumors.
Nine of the 12 nonbenign characters had more than 50% of high-intensity areas on T2-weighted images (T2WI), and some hyperintense foci on T1-weighted images (T1WI). In the contrast study, nine of 12 nonbenign characters had well-demarcated unenhanced areas. On the other hand, only two of 12 benign characters showed such a signal intensity pattern, and none of them had a pocket-like unenhanced area.
Although there were some exceptions, more than 50% of high signal on T2WI, and the presence of any small high-signal areas on T1WI with unenhanced pockets were considered MR-suggestive for SMTUMPs and leiomyosarcomas.
研究非良性子宫平滑肌肿瘤的磁共振（MR）特征。
本研究纳入9例经病理证实的平滑肌肉瘤患者和3例恶性潜能不确定的平滑肌肿瘤（SMTUMP）患者。还分析了12例妇科医生怀疑为平滑肌肉瘤的良性子宫平滑肌瘤及其变异型病例。对每例病例，我们研究了肿瘤的大小、位置、信号强度和对比增强情况。
12例非良性病变中有9例在T2加权像（T2WI）上有超过50%的高强度区域，在T1加权像（T1WI）上有一些高信号灶。在对比增强研究中，12例非良性病变中有9例有边界清晰的无强化区域。另一方面，12例良性病变中只有2例表现出这样的信号强度模式，且均无囊状无强化区域。
尽管存在一些例外情况，但T2WI上超过50%的高信号以及T1WI上存在任何小的高信号区域且伴有无强化囊腔被认为是SMTUMP和平滑肌肉瘤的MR提示特征。
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