Prayson R A, Hart W R
Department of Anatomic Pathology, Cleveland Clinic Foundation, Ohio 44195, USA.
Obstet Gynecol Clin North Am. 1995 Dec;22(4):637-57.
Smooth muscle tumors are the most common type of uterine neoplasm. The vast majority of such tumors are benign leiomyomas. Leiomyosarcomas fortunately are relatively infrequent. A variety of gross and microscopic features may be found in both benign and malignant tumors and great care must be taken not to mistake leiomyomas with atypical or unusual features of leiomyosarcomas. Individual features, such as hypercellularity, necrosis, nuclear atypia, mitotic figures, and intravascular growth, are ominous but must be interpreted with caution because variants of benign leiomyoma may contain such changes.
平滑肌瘤是最常见的子宫肿瘤类型。这类肿瘤绝大多数是良性的平滑肌瘤。幸运的是，平滑肌肉瘤相对少见。良性和恶性肿瘤都可能有多种大体和显微镜下特征，必须格外小心，以免将具有平滑肌肉瘤非典型或异常特征的平滑肌瘤误诊。个别特征，如细胞增多、坏死、核异型性、核分裂象和血管内生长等，虽不吉利，但必须谨慎解读，因为良性平滑肌瘤的变体可能包含此类变化。
