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[福尼尔坏疽]

[Fournier's gangrene].

作者信息

Pawłowski Waldemar, Wroński Marek, Krasnodebski Ireneusz W

机构信息

Katedra i Klinika Chirurgii Ogólnej, Gastroenterologicznej i Zywienia AM w Warszawie.

出版信息

Pol Merkur Lekarski. 2004 Jul;17(97):85-7.

Abstract

Fournier's gangrene is a necrotizing fasciitis of the genital and scrotal region due to infectious process. The gangrene is rare. Most cases are diagnosed in elderly patients with immunodeficiency, especially in diabetics or alcoholics. Currently a primary infection focus can be revealed in about 95% cases. The nidus is usually located in the genitourinary tract, lower gastrointestinal tract or skin. Fournier's gangrene is a mixed infection caused by both aerobic and anaerobic bacterial flora. The development and progression of the gangrene is often fulminating and can rapidly cause multiple organ failure and death. Early surgical debridement of necrotic tissues and antibiotics are fundamental in the treatment of Fournier's gangrene. Despite of advanced management mortality is still high and averages 20-30%.

摘要

福尼尔坏疽是一种因感染过程导致的生殖器和阴囊区域的坏死性筋膜炎。这种坏疽较为罕见。大多数病例在免疫功能低下的老年患者中被诊断出来,尤其是糖尿病患者或酗酒者。目前,约95%的病例能够发现原发性感染病灶。病灶通常位于泌尿生殖道、下消化道或皮肤。福尼尔坏疽是由需氧菌和厌氧菌菌群引起的混合感染。坏疽的发展和进展通常迅猛,可迅速导致多器官功能衰竭和死亡。早期对坏死组织进行外科清创和使用抗生素是治疗福尼尔坏疽的根本。尽管治疗手段先进,但死亡率仍然很高,平均为20% - 30%。

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