Morais Henrique, Neves Jessica, Maciel Ribeiro Hugo, Ferreira Marta, Guimarães Narcisa, Azenha Nuno, Dias Raquel, Fonseca Alice, Conceição Lucilia
Department of Surgery, Hospital Distrital da Figueira da Foz, 3094-001, Figueira da Foz, Portugal.
Ann Med Surg (Lond). 2017 Feb 27;16:19-22. doi: 10.1016/j.amsu.2017.02.043. eCollection 2017 Apr.
Identifying the factors affecting the outcome of patients with Fournier's Gangrene and assaying the accuracy of the Fournier Gangrene Severity Index (FGIS), the Uludag score (UdS), affected Body Surface Area (BSA) and the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) model as prognostic tools.
Retrospective study involving all patients with Fournier's gangrene treated in our Hospital between January 2008 and December 2015. The epidemiological, clinical, biochemical and management data of these patients was obtained and analyzed.
The series includes 19 patients, 14 male and 5 female, with a median age of 70 (62; 78,5) years. The mortality rate was 21%. From the data analyzed, only the affected BSA (BSA>3.25%) was associated with mortality (p = 0.016). None of the established scores (FGSI; UdS; LRINEC) proved to be a useful tool for predicting mortality. The combination of affected BSA and FSGI (FGSI≥9 or BSA>3.25%), (p = 0.004) and the combination of the affected BSA and the LRINEC model (LRICEC≥8 and BSA>3.25%), (p = 0.004) led to a major improvement in these scores.
Affected BSA is a useful prognostic factor in Fournier's gangrene. The existing prognostic scores can be improved with the introduction of this factor.
确定影响福尼尔坏疽患者预后的因素,并分析福尼尔坏疽严重程度指数(FGIS)、乌鲁达格评分(UdS)、受影响体表面积(BSA)和坏死性筋膜炎实验室风险指标(LRINEC)模型作为预后工具的准确性。
回顾性研究2008年1月至2015年12月在我院接受治疗的所有福尼尔坏疽患者。获取并分析这些患者的流行病学、临床、生化和治疗数据。
该系列包括19例患者,14例男性和5例女性,中位年龄为70(62;78.5)岁。死亡率为21%。从分析的数据来看,只有受影响的体表面积(BSA>3.25%)与死亡率相关(p = 0.016)。没有一个既定的评分(FGSI;UdS;LRINEC)被证明是预测死亡率的有用工具。受影响的BSA与FSGI的组合(FGSI≥9或BSA>3.25%),(p = 0.004)以及受影响的BSA与LRINEC模型的组合(LRICEC≥8且BSA>3.25%),(p = 0.004)使这些评分有了显著改善。
受影响的BSA是福尼尔坏疽中一个有用的预后因素。引入该因素可改善现有的预后评分。