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[The effect of immunofan on the immunity system characteristics and lipid peroxidation parameters upon acute chemical poisoning].

作者信息

Zabrodskiĭ P F, Germanchuk V G, Nodel' M L, Vasilenko O A, Aredakov A N

出版信息

Eksp Klin Farmakol. 2004 Sep-Oct;67(5):28-30.

Abstract

The results of experiments on Wistar rats under conditions of acute poisoning with 0.75 LD50 of zarin (isopropylmethyl fluorophosphonate), luisite (beta-chlorovinyl dichloroarsine), arsenic chloride, and dichloroethane showed that a four-day treatment with immunofan in a dose of 10 microg/kg restored the immune status characteristics (antibody formation to T-dependent antigen, antibody-dependent cell-mediated cytotoxicity, natural killer cell activity, and delayed type hypersensitivity) and the related LPO parameters.

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