Zabrodskiĭ P F, Romashchenko S A
Department of Toxicology, Saratov State Medical University, Russia.
Eksp Klin Farmakol. 1998 Sep-Oct;61(5):56-8.
Experiments on noninbred Wistar mice and rats showed that acute acrylonitrile (0.5 LD50) intoxication leads to decrease of nonspecific resistance of the organism and humoral and cellular immunity responses. The antidote sodium thiosulfate increases suppression of the responses under study.