Madden Brendan P, Park John E S, Sheth Abhijat
Department of Cardiothoracic Surgery, St. George's Hospital, London, England, UK.
Ann Thorac Surg. 2004 Dec;78(6):1898-902. doi: 10.1016/j.athoracsur.2004.05.062.
Between March 1997 and March 2004 we deployed 80 Ultraflex metallic expandable stents (Boston Scientific, Waterson, MA) in 69 patients under direct vision using rigid bronchoscopy. We report our medium- to long-term experience in patients for whom these stents were deployed.
To date 15 patients have been followed for more than 1 year (median 41 months, range 12 to 83 months) after stent deployment. Indications for stenting in these patients were neoplasia (5), stricture (5), airway malacia (1), iatrogenic tracheal tear (1), and compression from an aortic aneurysm (1), a right interrupted aortic arch (1), and a right brachiocephalic artery aneurysm with tracheomalacia (1). Ten tracheal stents (9 covered, 1 uncovered) and 10 bronchial stents (8 uncovered, 2 covered) were inserted, and 5 patients received two stents.
Five of these patients experienced no long-term problems. Complications included troublesome halitosis (5), which was difficult to treat despite various antibiotic regimes; granulation tissue formation above and below the stent that was successfully treated with low-power Nd:YAG laser therapy (7); and metal fatigue (1). We did not encounter stent migration.
We conclude that Ultraflex expandable metallic stents have an important role in the management of selected patients with diverse endobronchial pathologies and are well tolerated in the long-term. Although associated granulation tissue can be successfully treated with Nd:YAG laser, halitosis can be a difficult problem to address.
1997年3月至2004年3月期间,我们在69例患者中使用硬质支气管镜直视下植入了80枚Ultraflex金属可扩张支架(波士顿科学公司,马萨诸塞州沃特敦)。我们报告了这些支架植入患者的中长期经验。
迄今为止,15例患者在支架植入后已随访超过1年(中位时间41个月,范围12至83个月)。这些患者的支架植入适应症包括肿瘤(5例)、狭窄(5例)、气道软化(1例)、医源性气管撕裂(1例)以及主动脉瘤压迫(1例)、右位主动脉弓中断(1例)和伴有气管软化的右头臂动脉瘤(1例)。共插入10枚气管支架(9枚带覆膜,1枚不带覆膜)和10枚支气管支架(8枚不带覆膜,2枚带覆膜),5例患者接受了两枚支架植入。
其中5例患者未出现长期问题。并发症包括令人困扰的口臭(5例),尽管采用了各种抗生素治疗方案仍难以治愈;支架上下方肉芽组织形成,采用低功率钕:钇铝石榴石激光治疗成功(7例);以及金属疲劳(1例)。我们未遇到支架移位情况。
我们得出结论,Ultraflex可扩张金属支架在治疗某些患有多种支气管内病变的患者中具有重要作用,并且长期耐受性良好。尽管相关的肉芽组织可用钕:钇铝石榴石激光成功治疗,但口臭可能是一个难以解决的问题。