Nürnberg Jan Hendrik, Ovroutski Stanislav, Alexi-Meskishvili Vladimir, Ewert Peter, Hetzer Roland, Lange Peter E
Department of Congenital Heart Disease/Pediatric Cardiology, German Heart Institute Berlin, Berlin, Germany.
Ann Thorac Surg. 2004 Dec;78(6):1979-88; discussion 1988. doi: 10.1016/j.athoracsur.2004.02.107.
Arrhythmias are one of the main causes of postoperative morbidity superseding Fontan operations. Comparative data on the incidence of sinus node dysfunction after the extracardiac Fontan operation (ECFO) and the intraatrial lateral tunnel Fontan operation (LTFO) are very limited and controversial. The aim of this study was to evaluate whether ECFO decreases the risk of postoperative arrhythmias compared with LTFO.
Seventy-four consecutive patients received either an LTFO (n = 29, 5 recordings in 1992 to 9 recordings in 1997) or an ECFO (n = 45, 11 recordings in 1995 to 5 recordings in 2001). The rhythm was documented preoperatively and postoperatively with standard electrocardiogram (ECG) recording and ECG monitoring. During follow-up all patients had 2-8 (median 3) standard ECG recordings per year. Additionally 45 patients (65%) had a Holter ECG at least once a year.
Median follow-up post-ECFO was 4.4 years (1.6-7.2) and post-LTFO it was 7.9 years (5.4-11.1). There were 5 early deaths (3 LTFO, 2 ECFO) and 1 late death (LTFO) (total mortality 8%). Sinus rhythm persisted in 37 ECFO patients (86%) as compared with 13 LTFO patients (50%) (p < 0.001). The incidence of new onset supraventricular tachyarrhythmias (SVTs) post-ECFO compared with LTFO was lower: 5 patients (11%) versus 11 patients (38%) early postoperatively (p < 0.001) and none versus 7 patients (27%) during follow-up (p < 0.001), respectively. Early postoperatively 10 LTFO patients (34%) and another 3 patients during follow-up required permanent pacemaker implantation due to bradyarrhythmias, but none of the ECFO patients required this.
Our data suggest that ECFO decreases the incidence of postoperative new onset arrhythmias during early and midterm follow-up compared with LTFO.
心律失常是法洛四联症术后发病的主要原因之一。关于心外膜法洛四联症手术(ECFO)和心房内隧道法洛四联症手术(LTFO)后窦房结功能障碍发生率的比较数据非常有限且存在争议。本研究的目的是评估与LTFO相比,ECFO是否能降低术后心律失常的风险。
连续74例患者接受了LTFO(n = 29,1992年5例记录至1997年9例记录)或ECFO(n = 45,1995年11例记录至2001年5例记录)。术前和术后通过标准心电图(ECG)记录和ECG监测记录心律。在随访期间,所有患者每年进行2 - 8次(中位数3次)标准ECG记录。此外,45例患者(65%)每年至少进行一次动态心电图检查。
ECFO术后中位随访时间为4.4年(1.6 - 7.2年),LTFO术后为7.9年(5.4 - 11.1年)。有5例早期死亡(3例LTFO,2例ECFO)和1例晚期死亡(LTFO)(总死亡率8%)。37例ECFO患者(86%)维持窦性心律,而LTFO患者为13例(50%)(p < 0.001)。与LTFO相比,ECFO术后新发室上性快速心律失常(SVT)的发生率较低:术后早期分别为5例(11%)对11例(38%)(p < 0.001),随访期间分别为0例对7例(27%)(p < 0.001)。术后早期10例LTFO患者(34%)以及随访期间另外3例患者因缓慢性心律失常需要植入永久性起搏器,但ECFO患者均无需植入。
我们的数据表明,与LTFO相比,ECFO在早期和中期随访期间可降低术后新发心律失常的发生率。