Okutan Oguzhan, Kartaloglu Zafer, Ilvan Ahmet, Kunter Erdogan, Cerrahoglu Kamil, Capraz Firuz
GATA Camilica Chest Diseases Hospital - Istanbul, Turkey.
Bull Cancer. 2004 Jun;91(6):E201-10.
Lung cancer is still the most frequently seen malignancy among males where as females are less affected. Recently the lung cancer prevalence has been reported to increase among females in parallel to the increment in cigarette consumption. In our 2 clinic 11.2% (44 cases) of 393 primary lung cancer cases between 1993-1997 were female. We evaluated the demographical characteristics and yearly distribution of our female patients. Mean age was 64+/-12.1 and 18.2% of the patients were smokers. The main complaints were dyspnoea (59%), chest pain (57%), fatigue (47%), cough (45%)and sputum production (32%). The cell type distribution rates were as follows;adenocarcinoma 45.4%, squamous cell cancer 29.5%, small cell cancer 20.5% and large cell cancer 4.6%. The diagnostic methods used were sputum cytology (27.3%),transbronchial biopsy and lavage (38.6%), thoracocentesis and pleural biopsy (15.8%),transthoracic fine needle aspiration (13,6%) and open lung biopsy (4.7%). As a result,we found a low percentage of smokers but a high rate of adenocarcinomas among our female patients.
肺癌仍是男性中最常见的恶性肿瘤,而女性受影响较小。最近有报道称,随着女性吸烟量的增加,女性肺癌患病率也在上升。在我们两家诊所1993 - 1997年间的393例原发性肺癌病例中,11.2%(44例)为女性。我们评估了女性患者的人口统计学特征和年度分布情况。平均年龄为64±12.1岁,18.2%的患者吸烟。主要症状为呼吸困难(59%)、胸痛(57%)、疲劳(47%)、咳嗽(45%)和咳痰(32%)。细胞类型分布率如下:腺癌45.4%、鳞状细胞癌29.5%、小细胞癌20.5%和大细胞癌4.6%。所采用的诊断方法有痰细胞学检查(27.3%)、经支气管活检和灌洗(38.6%)、胸腔穿刺和胸膜活检(15.8%)、经胸细针穿刺抽吸(13.6%)和开胸肺活检(4.7%)。结果,我们发现女性患者中吸烟率较低,但腺癌发生率较高。