Abrams G A, Fallon M B
UAB Liver Center, Division of Gastroenterology and Hepatology, University of Alabama at Birmingham, Birmingham, Alabama 35294-0007, USA.
Clin Liver Dis. 1997 May;1(1):185-200, xiii. doi: 10.1016/s1089-3261(05)70263-4.
The hepatopulmonary syndrome occurs in subjects with chronic liver disease and/or portal hypertension who develop intrapulmonary vasodilation resulting in arterial deoxygenation. Clinical and basic science studies investigating the pathophysiology of HPS are presented. A diagnostic algorithm is provided using contrast echocardiography, the lung perfusion scan, and pulmonary angiography. Medical therapy and experience with liver transplantation are reviewed.
肝肺综合征发生于患有慢性肝病和/或门静脉高压的患者,这些患者会出现肺内血管扩张,导致动脉血氧合不足。本文介绍了研究肝肺综合征病理生理学的临床和基础科学研究。提供了一种使用对比超声心动图、肺灌注扫描和肺血管造影的诊断算法。回顾了药物治疗和肝移植经验。