前列腺的相控阵磁共振成像与根治性前列腺切除术标本的相关性：本地经验
Phased-array magnetic resonance imaging of the prostate with correlation to radical prostatectomy specimens: local experience.
作者信息
Kwek Jin-Wei, Thng Choon-Hua, Tan Puay-Hoon, Yuen John Shyi-Peng, Khoo James Boon-Kheng, Quek Swee-Tian, Ho Juliana Teng-Swan, Tan Kim-Ping, Cheng Christopher Wai-Sam
机构信息
Department of Diagnostic Radiology, Tan Tock Seng Hospital, Singapore.
出版信息
Asian J Surg. 2004 Jul;27(3):219-24; discussion 225-6. doi: 10.1016/S1015-9584(09)60037-3.
PURPOSE
To evaluate local experience of phased-array magnetic resonance imaging (MRI) in the staging of locally advanced prostate carcinoma with comparison to clinical staging.
METHODS
The study population was 21 patients who underwent preoperative MRI with pelvic phased-array coils followed by radical prostatectomy. The MRI findings were correlated with completely embedded serially sliced and whole-mounted sections of the prostate gland and clinical staging.
RESULTS
Overall accuracy of 57.1% was obtained, with specificity of 90.0% and sensitivity of 27.3%. All but one case of locally advanced disease missed by MRI was microscopic. Clinical staging in these cases also achieved accuracy of 57.1%, specificity of 90.0% and sensitivity of 27.3%.
CONCLUSIONS
MRI with a phased-array coil has high specificity but low sensitivity for detection of extraprostatic disease. Phased-array MRI does not image microscopic tumour extension. It did not perform better than clinical staging and is not recommended for routine staging.
目的
评估相控阵磁共振成像（MRI）在局部晚期前列腺癌分期中的应用经验，并与临床分期进行比较。
方法
研究对象为21例患者，这些患者在接受根治性前列腺切除术前行盆腔相控阵线圈MRI检查。将MRI检查结果与前列腺完整包埋、连续切片及全层切片的结果以及临床分期进行对比。
结果
总体准确率为57.1%，特异性为90.0%，敏感性为27.3%。MRI漏诊的局部晚期疾病中，除1例为肉眼可见外，其余均为镜下可见。这些病例的临床分期准确率也为57.1%，特异性为90.0%，敏感性为27.3%。
结论
相控阵线圈MRI检测前列腺外疾病具有高特异性但低敏感性。相控阵MRI无法显示镜下肿瘤浸润。其表现并不优于临床分期，不建议用于常规分期。
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