Jonczak Luiza, Kamiński Dariusz, Pływaczewski Robert, Bednarek Michał, Zieliński Jan
II Klinika Chorób Płuc, Instytut Gruzlicy i Chorób Płuc w Warszawie, Warsaw, Poland.
Neurol Neurochir Pol. 2004 Sep-Oct;38(5):427-30.
A case of moderate obstructive sleep apnea in which effective treatment with continuous positive airway pressure did not reduce excessive daytime sleepiness was described. Polysomnography with tibial muscles activity recording revealed frequent periodic limb movements in sleep (PLMS) with sleep fragmentation. PLMS index was 13.6/h of sleep. Clonazepam combined with iron and magnesium supplementation reduced limb movements, excessive daytime sleepiness and improved the patient's mood. Causes of PLMS and treatment options are discussed. PLMS and restless legs syndrome (RLS) should be considered in the differential diagnosis of excessive daytime sleepiness.
描述了一例中度阻塞性睡眠呼吸暂停患者,持续气道正压通气有效治疗后日间过度嗜睡仍未减轻。伴有胫骨肌活动记录的多导睡眠图显示睡眠中频繁出现周期性肢体运动(PLMS)及睡眠片段化。PLMS指数为每小时睡眠13.6次。氯硝西泮联合补充铁和镁减少了肢体运动、日间过度嗜睡并改善了患者情绪。讨论了PLMS的病因及治疗选择。在日间过度嗜睡的鉴别诊断中应考虑PLMS和不宁腿综合征(RLS)。