Glikson Michael, Gurevitz Osnat T, Trusty Jane M, Sharma Vinod, Luria David M, Eldar Michael, Shen Win-Kuang, Rea Robert F, Hammill Stephen C, Friedman Paul A
Sheba Medical Center and Tel Aviv University, Tel Hashomer, Israel.
Am J Cardiol. 2004 Dec 1;94(11):1445-9. doi: 10.1016/j.amjcard.2004.07.151.
The defibrillation threshold (DFT) and upper limit of vulnerability (ULV) were determined using step-down protocols in 50 patients who underwent implantable cardioverter-defibrillator placement or testing. The sensitivity and specificity of each ULV energy level was assessed for detecting an increased DFT, correlation of the DFT and ULV, and optimal shock timing for ULV determination. A ULV <10 or 11 J (failure to induce ventricular fibrillation with 10- to 11-J shocks) was 100% predictive of an acceptable DFT and may be sufficient to exclude unacceptable DFTs in 60% of implantable cardioverter-defibrillator recipients. All 4 shocks used to scan the peak of the T wave during ULV testing were necessary for accurate ULV determination.
采用逐步降低方案，对50例接受植入式心脏复律除颤器植入或测试的患者测定除颤阈值（DFT）和易损上限（ULV）。评估每个ULV能量水平检测DFT升高的敏感性和特异性、DFT与ULV的相关性以及确定ULV的最佳电击时机。ULV<10或11 J（10至11 J电击未能诱发心室颤动）对可接受的DFT具有100%的预测性，可能足以排除60%的植入式心脏复律除颤器接受者中不可接受的DFT。在ULV测试期间，用于扫描T波峰值的所有4次电击对于准确确定ULV都是必要的。
