Chamundeeswari D, Vasantha J, Gopalakrishnan S, Sukumar E
Sri Ramachandra College of Pharmacy, Sri Ramachandra Medical College and Research Institute (Deemed University), Porur, Chennai-600 116, India.
Fitoterapia. 2004 Dec;75(7-8):740-4. doi: 10.1016/j.fitote.2004.07.001.
The alcoholic extract of Trewia polycarpa roots, when administered orally to rats at doses of 50-400 mg/kg, exhibited a dose-dependent anti-inflammatory activity in both acute and chronic models. It also showed a significant antinociceptive action mice in the dose range of 25-200 mg/kg. The extract did not reveal any toxicity in rats up to a dose of 3.2 g/kg (p.o.). It showed the presence of terpenoids, alkaloids, flavonoids, quinones and glycosides on phytochemical screening.
多果三棱婆根的乙醇提取物，以50-400毫克/千克的剂量口服给予大鼠时，在急性和慢性模型中均表现出剂量依赖性抗炎活性。在25-200毫克/千克的剂量范围内，它对小鼠也显示出显著的镇痛作用。该提取物在高达3.2克/千克（口服）的剂量下对大鼠未显示出任何毒性。植物化学筛选表明其含有萜类、生物碱、黄酮类、醌类和糖苷。
