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老年患者全膝关节置换术中丙泊酚-脊髓麻醉与丙泊酚-芬太尼麻醉的麻醉质量比较。

A comparison of anesthetic quality in propofol-spinal anesthesia and propofol-fentanyl anesthesia for total knee arthroplasty in elderly patients.

作者信息

Kudoh Akira, Takase Hajime, Takazawa Tomoko

机构信息

Department of Anesthesiology, Hirosaki National Hospital, Hirosaki, Japan.

出版信息

J Clin Anesth. 2004 Sep;16(6):405-10. doi: 10.1016/j.jclinane.2003.10.003.

DOI:10.1016/j.jclinane.2003.10.003
PMID:15567642
Abstract

STUDY OBJECTIVE

To compare propofol plus spinal anesthesia during spontaneous ventilation using the Laryngeal Mask Airway and propofol plus fentanyl anesthesia during mechanical ventilation with an endotracheal tube on quality of recovery after anesthesia.

DESIGN

Prospective, randomized study.

SETTING

Hirosaki National Hospital.

PATIENTS

150 patients (aged > 70 years) undergoing total knee arthroplasty.

INTERVENTIONS

Patients were divided randomly into two groups, to receive spontaneous ventilation with a Laryngeal Mask Airway during propofol-spinal anesthesia, or to receive propofol-fentanyl anesthesia with mechanical ventilation via endotracheal tube.

MEASUREMENTS

Quality of anesthesia recovery such as nausea, vomiting, headache, pain throat, hoarse voice, back pain, dizziness, feeling comfortable, dreaming, recovery times in recovery of anesthesia, recovery times, postoperative pain, confusion, was assessed.

MAIN RESULTS

The frequency of postoperative pain throat, hoarse voice, and nausea was significantly lower in the propofol-spinal anesthesia group than the propofol-fentanyl anesthesia group. The time to extubation, emergence, response to commands, and orientation were significantly faster (p < 0.001) in the propofol-spinal anesthesia group than the propofol-fentanyl anesthesia group. The frequency of postoperative confusion occurring in the propofol-spinal anesthesia group during the first 24 hours was significantly lower than that of the propofol-fentanyl anesthesia group (p = 0.03).

CONCLUSIONS

Propofol-spinal anesthesia provided better and faster recovery than did propofol-fentanyl anesthesia for elderly patients undergoing total knee arthroplasty.

摘要

研究目的

比较在自主通气时使用喉罩气道的丙泊酚加脊髓麻醉与在机械通气时使用气管内导管的丙泊酚加芬太尼麻醉对麻醉后恢复质量的影响。

设计

前瞻性随机研究。

地点

弘前国立医院。

患者

150例年龄大于70岁行全膝关节置换术的患者。

干预措施

患者被随机分为两组,一组在丙泊酚-脊髓麻醉期间使用喉罩气道进行自主通气,另一组在丙泊酚-芬太尼麻醉期间通过气管内导管进行机械通气。

测量指标

评估麻醉恢复质量,如恶心、呕吐、头痛、咽痛、声音嘶哑、背痛、头晕、感觉舒适、做梦、麻醉恢复时间、苏醒时间、术后疼痛、意识模糊等。

主要结果

丙泊酚-脊髓麻醉组术后咽痛、声音嘶哑和恶心的发生率显著低于丙泊酚-芬太尼麻醉组。丙泊酚-脊髓麻醉组的拔管时间、苏醒时间、对指令的反应时间和定向时间显著快于丙泊酚-芬太尼麻醉组(p<0.001)。丙泊酚-脊髓麻醉组术后24小时内发生意识模糊的频率显著低于丙泊酚-芬太尼麻醉组(p=0.03)。

结论

对于行全膝关节置换术的老年患者,丙泊酚-脊髓麻醉比丙泊酚-芬太尼麻醉提供更好更快的恢复。

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