Martin Benjamin L, Harland Richard M
Division of Genetics and Development, Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720-3204, USA.
Gene Expr Patterns. 2004 Dec;5(2):239-43. doi: 10.1016/j.modgep.2004.07.010.
We have investigated the expression patterns of two Xenopus laevis genes with similarity to mouse steel (sl) using whole-mount in situ hybridization. Areas of overlapping expression include the epidermis, stomodeum, proctodeum, and otic placodes. Xsl-1 is specifically expressed in the pronephros, neural tube, gil arches, and a superficial region of the somite, while Xsl-2 is in the ganglion and facial nerve projecting to visceral arch 3, the mandibular arch, and the clefts of anterior somites. Thus, both transcripts exhibit partially overlapping expression patterns, but their tissue distribution differs significantly from that of sl expression in the mouse and chicken.
我们使用整装原位杂交技术研究了非洲爪蟾中两个与小鼠Steel（Sl）基因相似的基因的表达模式。重叠表达区域包括表皮、口凹、泄殖腔和耳基板。Xsl-1在原肾、神经管、鳃弓和体节的一个浅表区域特异性表达，而Xsl-2则在投射到第3内脏弓、下颌弓和前体节裂隙的神经节和面神经中表达。因此，这两种转录本都表现出部分重叠的表达模式，但它们的组织分布与小鼠和鸡中Sl基因的表达有显著差异。
