Xu Qing, Chen Wen-Hua, Huang Qing-Juan
Department of Radiology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Hepatobiliary Pancreat Dis Int. 2004 Nov;3(4):616-9.
Surgeons are always concerned about the localization of pancreatic functioning islet cell tumor. If the tumor is accurately localized before operation, resection of the pancreatic body and tail without intention can be avoided. The purpose of this study was to evaluate spiral CT localization of pancreatic functioning islet cell tumors and CT techniques.
CT manifestations in 6 patients with clinically and pathologically proved pancreatic functioning islet cell tumors were analyzed retrospectively.
In 4 patients with insulinomas and 2 patients with glucagonomas, 5 were localized accurately by CT before surgery and 1 was detected retrospectively. The enhancement of tumors was greater than that of normal pancreas in arterial phase and pancreatic parenchymal phase. Four patients showed mild high-density and 2, iso-density in the portal venous phase.
Spiral CT multi-phase enhanced scan with 1.5 ml/kg contrast agent and 2-5 mm slice width can localize functioning islet cell tumors accurately.
外科医生一直关注胰腺功能性胰岛细胞瘤的定位。如果在手术前肿瘤能被准确地定位，就可以避免无意中切除胰体和胰尾。本研究的目的是评估胰腺功能性胰岛细胞瘤的螺旋CT定位及CT技术。
回顾性分析6例经临床及病理证实的胰腺功能性胰岛细胞瘤患者的CT表现。
4例胰岛素瘤患者和2例胰高血糖素瘤患者中，5例术前CT准确定位，1例为术后回顾性发现。肿瘤在动脉期和胰腺实质期的强化程度高于正常胰腺。4例患者在门静脉期表现为轻度高密度，2例为等密度。
采用1.5ml/kg造影剂、层厚2 - 5mm的螺旋CT多期增强扫描可准确对功能性胰岛细胞瘤进行定位。
