Butler Tracy, Hirsch Lawrence J, Claassen Jan
Functional Neuroimaging Laboratory, Weill Medical College of Cornell University, New York, NY, USA.
BMC Nucl Med. 2004 Nov 29;4(1):2. doi: 10.1186/1471-2385-4-2.
Single photon emission computed tomography (SPECT) following injection of radiotracer during a seizure is known as ictal SPECT. Comparison of an ictal SPECT study to a baseline or interictal study can aid identification of a seizure focus. CASE PRESENTATION: A young woman with encephalitis and refractory seizures underwent brain SPECT during a period of frequent seizure-like episodes, and during a seizure-free period. A focal area of increased radiotracer uptake present only when she was experiencing frequent seizure-like episodes was originally localized to the brainstem, but with later computerized co-registration of SPECT to MRI, was found to lie outside the brain, in the region of the sphenoid sinus. CONCLUSION: Low-resolution SPECT images present difficulties in interpretation, which can be overcome through co-registration to higher-resolution structural images.
在癫痫发作期间注射放射性示踪剂后的单光子发射计算机断层扫描（SPECT）被称为发作期SPECT。将发作期SPECT研究与基线或发作间期研究进行比较有助于识别癫痫病灶。病例介绍：一名患有脑炎和难治性癫痫的年轻女性在频繁出现癫痫样发作期间以及无癫痫发作期间接受了脑部SPECT检查。仅在她频繁出现癫痫样发作时出现的放射性示踪剂摄取增加的局灶性区域最初定位于脑干，但后来通过SPECT与MRI的计算机联合配准，发现位于脑外蝶窦区域。结论：低分辨率SPECT图像在解读上存在困难，可通过与高分辨率结构图像联合配准来克服。
