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预防急性内科患者的静脉血栓栓塞症

Preventing venous thromboembolism in acute medical patients.

作者信息

Elis A, Ellis M H

机构信息

Department of Medicine 'A', Sapir Medical Center, Meir Hospital, 44281 Kfar Saba, Israel.

出版信息

QJM. 2004 Dec;97(12):797-801. doi: 10.1093/qjmed/hch128.

Abstract

BACKGROUND

While extensive data support the clinical benefit and cost-effectiveness of routine thromboprophylaxis in surgical patients, the use of this approach in medical patients has been controversial. However, recent data, mainly from the MEDENOX trial, support routine thromboprophylaxis in acutely ill medical patients.

AIM

To determine attitudes towards VTE prevention in such patients, in departments of internal medicine in Israel.

DESIGN

Questionnaire-based survey.

METHODS

A questionnaire regarding aspects of VTE prophylaxis was mailed to all heads of internal medicine departments in Israel (n = 90). The questionnaire also included data concerning VTE prevention measures in specific acute medical illnesses, based on the MEDENOX study population.

RESULTS

Fifty-eight (64%) departments returned the questionnaire. Forty-seven (81%) of them considered VTE a clinical problem in their departments, but only 37 (63%) had a routine VTE prevention policy. The most frequently used modality for VTE prophylaxis was low-molecular-weight heparin. There was little agreement concerning the exact indications or risk factors in which VTE prophylaxis measures should be used, except the combination of acute medical disabling illness and previous VTE.

DISCUSSION

The results emphasize the need for detailed guidelines and risk assessment models for VTE prevention treatments in acutely ill medical patients, as well as better education for physicians.

摘要

背景

尽管大量数据支持外科手术患者常规血栓预防的临床益处和成本效益,但这种方法在内科患者中的应用一直存在争议。然而,最近的数据,主要来自MEDENOX试验,支持对急性病内科患者进行常规血栓预防。

目的

确定以色列内科各科室对此类患者预防静脉血栓栓塞(VTE)的态度。

设计

基于问卷的调查。

方法

向以色列所有内科科室主任(n = 90)邮寄了一份关于VTE预防各方面的问卷。该问卷还包括基于MEDENOX研究人群的特定急性内科疾病中VTE预防措施的数据。

结果

58个科室(64%)回复了问卷。其中47个科室(81%)认为VTE是其科室的临床问题,但只有37个科室(63%)有常规的VTE预防政策。最常用的VTE预防方式是低分子肝素。除了急性内科致残性疾病和既往VTE外,对于应采取VTE预防措施的确切指征或危险因素,几乎没有一致意见。

讨论

结果强调需要为急性病内科患者的VTE预防治疗制定详细的指南和风险评估模型,以及对医生进行更好的教育。

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