Suzuki Hideki, Watanabe Hideomi, Shinozaki Tetsuya, Yanagawa Takashi, Suzuki Ryoko, Takagishi Kenji
Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma 371-8511, Japan.
J Shoulder Elbow Surg. 2004 Nov-Dec;13(6):635-47. doi: 10.1016/j.jse.2004.03.015.
The shoulder girdle presents unique features for the preoperative planning of musculoskeletal tumors. This is the first trial to evaluate positron emission tomography (PET) analysis for preoperative planning in shoulder girdle tumors. Fifty-two patients were examined with fluorine 18 fluoro-2-deoxy-D-glucose (FDG)-PET and/or alpha-methyltyrosine (FMT)-PET. Imaging findings were visually inspected in conjunction with computed tomography and/or magnetic resonance imaging, and standardized uptake values (SUVs) were generated. FDG-PET may be useful for the detection of malignant tumors and screening for metastatic spread, with the qualitative assessment of heterogeneous biologic activity providing a correct approach for biopsy. The mean SUVs for malignant tumors were significantly higher than those for benign lesions. However, a useful cutoff SUV was not found in either FDG- or FMT-PET for differentiating malignant from benign tumors from receiver operating characteristic curve analysis. SUVs on FDG- and FMT-PET may merely be limited to differentiating malignant from benign tumors in the shoulder girdle.
肩胛带在肌肉骨骼肿瘤的术前规划方面具有独特特征。这是评估正电子发射断层扫描（PET）分析在肩胛带肿瘤术前规划中应用的首个试验。52例患者接受了氟18氟 - 2 - 脱氧 - D - 葡萄糖（FDG） - PET和/或α - 甲基酪氨酸（FMT） - PET检查。结合计算机断层扫描和/或磁共振成像对影像结果进行了视觉检查，并生成了标准化摄取值（SUVs）。FDG - PET对于恶性肿瘤的检测和转移扩散的筛查可能有用，对异质性生物活性的定性评估为活检提供了正确方法。恶性肿瘤的平均SUVs显著高于良性病变。然而，从受试者工作特征曲线分析来看，在FDG - 或FMT - PET中均未发现用于区分恶性肿瘤与良性肿瘤的有用SUV临界值。FDG - 和FMT - PET上的SUVs可能仅局限于区分肩胛带中的恶性肿瘤与良性肿瘤。
