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[骨质量评估——现状与未来]

[Assessment of bone quality--present and future].

作者信息

Ito Masako

机构信息

Division of Radiology, Nagasaki University Hospital.

出版信息

Clin Calcium. 2004 Dec;14(12):27-32.

PMID:15577170
Abstract

Bone quality including "structural property" and "material property" , which is strongly affected by bone remodeling and has an influence on bone biomechanical property. Structural property means macroscopical geometry, bone size, trabecular microstructure, cortical thickness and cortical porosity. Material property means mineralization, crystal size, collagen and microdamage. Although most of them are analyzed in vitro, in the future, noninvasive assessment of bone quality may help to guide therapy of osteoporosis.

摘要

骨质量包括“结构特性”和“材料特性”,其受到骨重塑的强烈影响,并对骨生物力学特性产生影响。结构特性指宏观几何形状、骨大小、小梁微结构、皮质厚度和皮质孔隙率。材料特性指矿化、晶体大小、胶原蛋白和微损伤。尽管其中大多数是在体外进行分析的,但未来,骨质量的无创评估可能有助于指导骨质疏松症的治疗。

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