Tanaka Ikuko, Oshima Hisaji
Department of Laboratory Medicine, Fujita Health University School of Medicine.
Clin Calcium. 2004 Dec;14(12):77-82.
While the diagnosis and management of primary osteoporosis have been established and widely utilized, these for glucocorticoid-induced osteoporosis (GIOP), i.e. a representative of secondary osteoporosis, are on their way. GIOP caused fractures at a higher bone mineral density (BMD) compared to primary osteoporosis. The cut off value of the BMD for prediction of fractures was around 80% of the young adult means (T-score; -1.5). As this value would give a useful diagnostic point for initiating treatments, measurements of BMD should be a significant tool for management of GIOP.
虽然原发性骨质疏松症的诊断和管理方法已经确立并得到广泛应用,但对于糖皮质激素性骨质疏松症(GIOP),即继发性骨质疏松症的一种典型类型,其诊断和管理方法仍在不断发展中。与原发性骨质疏松症相比,GIOP在骨矿物质密度(BMD)较高时就会导致骨折。预测骨折的BMD临界值约为年轻成年人平均值的80%(T值;-1.5)。由于该值可为开始治疗提供有用的诊断依据,因此BMD测量应成为GIOP管理的一项重要工具。