Klerkx M P, van Son J A, Laquet L K, Daniëls O
Afd. Kindercardiologie, Academisch Ziekenhuis Nijmegen.
Tijdschr Kindergeneeskd. 1992 Feb;60(1):6-10.
This article describes a retrospective investigation concerning the occurrence of hypertension in 65 patients who, between 1975 and 1990, underwent surgical repair of coarctation of the aorta. The objective of the study was to investigate the incidence of hypertension after operative correction of coarctation of the aorta. In addition an attempt was made to find a correlation between recoarctation, age at surgery, surgical technique and associated intracardiac malformations, and the presence of persistent postoperative or late occurring hypertension. Eighteen of the 65 patients (27.7%) appeared to be hypertensive 3 to 13 years (mean 5.2 years) after the operation. In only 3 patients hypertension could be explained by restenosis at the coarctation repair site. In 60% and 34.3% of the patients a correlation existed with the presence of a hypoplastic aortic arch and serious additional intracardiac anomalies, respectively. On the basis of these findings early operative treatment of coarctation of the aorta seems to be indicated, especially when the coarctation is associated with hypoplasia of the aortic arch or with complex intracardiac anomalies. Because of the relative small number of patients that underwent operative correction of coarctation of the aorta beyond the first year of life a correlation between the postoperative occurrence of hypertension and the age at operation was not found.
本文描述了一项回顾性调查，涉及1975年至1990年间接受主动脉缩窄手术修复的65例患者中高血压的发生情况。该研究的目的是调查主动脉缩窄手术矫正后高血压的发生率。此外，还试图找出再缩窄、手术年龄、手术技术和相关心内畸形与术后持续性或晚期高血压之间的相关性。65例患者中有18例（27.7%）在术后3至13年（平均5.2年）出现高血压。只有3例患者的高血压可归因于缩窄修复部位的再狭窄。分别有60%和34.3%的患者高血压与主动脉弓发育不全和严重的额外心内异常有关。基于这些发现，似乎有必要对主动脉缩窄进行早期手术治疗，尤其是当缩窄与主动脉弓发育不全或复杂的心内畸形相关时。由于在生命的第一年之后接受主动脉缩窄手术矫正的患者数量相对较少，因此未发现术后高血压的发生与手术年龄之间的相关性。
