Bender Bruce G, Bender Sarah E
Division of Pediatric Behavioral Health, National Jewish Medical and Research Center, 1400 Jackson Street, Denver, CO 80206, USA.
Immunol Allergy Clin North Am. 2005 Feb;25(1):107-30. doi: 10.1016/j.iac.2004.09.005.
This article reviews 32 patient-interview studies that revealed that the most common barriers to adherence revealed by patients included concerns about drug safety and cost and a belief that the patient's asthma was not severe enough to require daily treatment. Important but less commonly cited concerns included worry about dependence or diminished effectiveness with long-term use of the medication. Children and their parents expressed concerns about safety, dependence, peer stigmatization, and parent-child conflict over taking medication. Low-income and minority patients cited similar concerns and barriers that included cost, difficulty of obtaining medication, daily life hassles, and a general distrust of the medical establishment. The information obtained from patients' perspectives indicates the need to reappraise current strategies for the management of asthma, including a more flexible approach to the use of expert guidelines for the treatment of asthma.
本文回顾了32项患者访谈研究,这些研究表明,患者所揭示的最常见的依从性障碍包括对药物安全性和成本的担忧,以及认为患者的哮喘病情不够严重,无需每日治疗。重要但较少被提及的担忧包括对长期使用药物产生依赖性或有效性降低的担心。儿童及其父母表达了对安全性、依赖性、同伴污名化以及服药方面亲子冲突的担忧。低收入和少数族裔患者提到了类似的担忧和障碍,包括成本、获取药物困难、日常生活困扰以及对医疗机构的普遍不信任。从患者角度获得的信息表明,有必要重新评估当前的哮喘管理策略,包括对哮喘治疗专家指南采取更灵活的应用方法。