Ment Laura R, Vohr Betty R, Makuch Robert W, Westerveld Michael, Katz Karol H, Schneider Karen C, Duncan Charles C, Ehrenkranz Richard, Oh William, Philip Alistair G S, Scott David T, Allan Walter C
Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA.
J Pediatr. 2004 Dec;145(6):832-4. doi: 10.1016/j.jpeds.2004.07.035.
Our multicenter Indomethacin Intraventricular Hemorrhage (IVH) Prevention Trial demonstrated a reduction of IVH in preterm infants. Analysis of our cohort by sex showed indomethacin halved the incidence of IVH, eliminated parenchymal hemorrhage, and was associated with higher verbal scores at 3 to 8 years in boys.
我们的多中心吲哚美辛预防脑室内出血(IVH)试验表明,早产婴儿的脑室内出血有所减少。按性别对我们的队列进行分析显示,吲哚美辛使脑室内出血的发生率减半,消除了实质出血,并且与男孩3至8岁时较高的语言评分相关。