一种用于糖酸的对映选择性荧光传感器。

An enantioselective fluorescent sensor for sugar acids.

作者信息

Zhao Jianzhang, Davidson Matthew G, Mahon Mary F, Kociok-Köhn Gabriele, James Tony D

机构信息

Department of Chemistry and Bath Chemical Crystallography, University of Bath, Bath BA2 7AY, UK.

出版信息

J Am Chem Soc. 2004 Dec 15;126(49):16179-86. doi: 10.1021/ja046289s.

DOI:10.1021/ja046289s

PMID:15584754

Abstract

Chiral fluorescent boronic acid 1 was found to be a highly enantioselective, chemoselective, and sensitive sensor for sugar acids, such as tartaric acid. Enantioselectivities (K(R)/K(S)) of up to 550:1, chemoselectivity up to 11,000:1, and sensitivities in the micromolar range with sensor 1 were observed. Single-crystal X-ray analysis was used to confirm the structure of the fluorescent species.

摘要

手性荧光硼酸1被发现是一种对酒石酸等糖酸具有高对映选择性、化学选择性和灵敏性的传感器。观察到传感器1的对映选择性（K(R)/K(S)）高达550:1，化学选择性高达11,000:1，且灵敏度处于微摩尔范围。单晶X射线分析用于确认荧光物质的结构。