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[糖尿病年轻患者中的意外及不明原因死亡]

[Unexpected and unexplained deaths among young patients with diabetes mellitus].

作者信息

Ramsli Håvard M, Therkelsen Stig Palm, Søvik Oddmund, Thordarson Hrafnkell

机构信息

Brattvåg legekontor, 6270 Brattvåg.

出版信息

Tidsskr Nor Laegeforen. 2004 Dec 2;124(23):3064-5.

Abstract

BACKGROUND

We studied the occurrence of unexpected and unexplained deaths in 0-39 year-old subjects with diabetes.

MATERIAL AND METHODS

Statistics Norway provided information about persons who had died in the 1991-1995 period with a diagnosis of diabetes on their death certificate. Relevant information was obtained from autopsy reports and patients' physicians.

RESULTS

117 deaths from all causes were ascertained. Four patients (3.4%) fulfilled the criteria of "dead in bed" syndrome; three males and one female, age range 21-36 years, duration of diabetes 5-23 years. Severe episodes of hypoglycaemia were reported in three cases. Autopsy, performed in three cases, was negative.

INTERPRETATION

Dead in bed syndrome in young persons with diabetes is a rare, but dramatic condition. The relationship to nocturnal hypoglycaemia remains hypothetical.

摘要

背景

我们研究了0至39岁糖尿病患者中意外和不明原因死亡的发生情况。

材料与方法

挪威统计局提供了1991年至1995年期间死亡证明上诊断为糖尿病的人员信息。相关信息从尸检报告和患者的医生处获得。

结果

确定了117例各种原因导致的死亡。4例患者(3.4%)符合“床上死亡”综合征标准;3名男性和1名女性,年龄范围21至36岁,糖尿病病程5至23年。3例报告有严重低血糖发作。3例进行了尸检,结果均为阴性。

解读

糖尿病青年患者的“床上死亡”综合征是一种罕见但严重的情况。与夜间低血糖的关系仍属假设。

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