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胸腔内注射自体羊水用于减胎术的成功案例:两例报告

Successful outcome of intrathoracic injection of autologous amniotic fluid in fetal reduction: report of two cases.

作者信息

Horng Shang-Gwo, Wang Chia-Woei, Huang Hong-Yuan, Soong Yoong-Kuei

机构信息

Department of Obstetrics and Gynecology, Chang-Gung Memorial Hospital, Taipei, Taiwan, Republic of China.

出版信息

J Assist Reprod Genet. 2004 Sep;21(9):343-5. doi: 10.1023/b:jarg.0000045475.90846.89.

Abstract

Potassium chloride is reported to kill both monochorionic twins after injection into only one. In this study, two women undergoing in vitro fertilization and embryo transfer were pregnant with triplets containing monochorionic twinning, which were detected by ultrasound with the presence of a "twin-peak" sign. Instead of potassium chloride, intrathoracic injection of amniotic fluid was employed to sacrifice one of the monochorionic fetuses in dichorionic triplets. Our aim was to sacrifice one of the monochorionic twins in order to prevent adverse perinatal outcomes and to avoid the harmful effect of potassium chloride on monochorionic cotwins. One twin pregnancy was terminated with preterm premature rupture of membranes at 25 weeks of gestation. In the second one, two healthy babies were delivered by cesarean section at 36 weeks of gestation. The female baby weighed 2100 gm and the male baby 2600 gm, respectively. Intrathoracic injection of amniotic fluid to create a tamponade is an alternative management for fetal reduction.

摘要

据报道,仅向单绒毛膜双胎中的一个注射氯化钾会导致两个胎儿均死亡。在本研究中,两名接受体外受精和胚胎移植的女性怀有三胞胎,其中包含单绒毛膜双胎,通过超声检查发现有“双峰”征。在双绒毛膜三胞胎中,采用胸腔内注射羊水而非氯化钾来牺牲其中一个单绒毛膜胎儿。我们的目的是牺牲其中一个单绒毛膜双胎,以预防围产期不良结局,并避免氯化钾对单绒毛膜双胎的有害影响。一例双胎妊娠在妊娠25周时因胎膜早破而终止。在另一例中,妊娠36周时通过剖宫产分娩出两名健康婴儿。女婴体重2100克,男婴体重2600克。胸腔内注射羊水以形成填塞是减胎的一种替代处理方法。

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