Chasen Stephen T, Al-Kouatly Huda B, Ballabh Praveen, Skupski Daniel W, Chervenak Frank A
Department of Obstetrics and Gynecology, Weill Medical College of Cornell University, New York, NY, USA.
Am J Obstet Gynecol. 2002 Apr;186(4):765-7. doi: 10.1067/mob.2002.122097.
The objective of this study was to describe outcomes in a series of dichorionic triplet pregnancies.
All triplet pregnancies evaluated in our obstetric sonography unit from 1993 to 2000 were identified. Those containing a monochorionic twin pair were included. Prenatal and neonatal records were reviewed. Statistical comparison was performed by using Wilcoxon matched-pairs signed-ranked sum test.
Seventeen cases met inclusion criteria. Two pregnancies (11.8%) were delivered spontaneously before viability, at 22 and 21 weeks. Twin-twin transfusion syndrome was diagnosed in the second trimester in the monochorionic pair in 3 pregnancies (17.6%). In the remaining 12 pregnancies, mean gestational age at delivery was 33.5 +/- 2.3 weeks. The median birth weight of 23 neonates from individual monochorionic twin pairs was 1810 g (interquartile range, 1540-2180 g), which was significantly lower than the median birth weight of 12 triplets supplied by a separate placenta, 2125 g (interquartile range, 1762-2390 g) (P =.01).
Twin-twin transfusion syndrome or spontaneous loss before viability complicated approximately 30% of dichorionic triplet pregnancies. Lower birth weights were noted in triplets from monochorionic twin pairs.
本研究的目的是描述一系列双绒毛膜三胎妊娠的结局。
确定了1993年至2000年在我们产科超声科接受评估的所有三胎妊娠。纳入那些包含单绒毛膜双胎对的妊娠。回顾产前和新生儿记录。采用Wilcoxon配对符号秩和检验进行统计学比较。
17例符合纳入标准。2例妊娠(11.8%)在可存活前自然分娩,分别为22周和21周。3例妊娠(17.6%)在孕中期诊断出单绒毛膜双胎对发生双胎输血综合征。在其余12例妊娠中,平均分娩孕周为33.5±2.3周。来自单个单绒毛膜双胎对的23例新生儿的中位出生体重为1810 g(四分位间距,1540 - 2180 g),显著低于由单独胎盘供应的12例三胎的中位出生体重2125 g(四分位间距,1762 - 2390 g)(P = 0.01)。
双胎输血综合征或可存活前自然流产使约30%的双绒毛膜三胎妊娠复杂化。单绒毛膜双胎对的三胎出生体重较低。