Dada-Adegbola H O, Bakare R A
Department of Medical Microbiology and Parasitology, University College Hospital, Ibadan, Oyo State, Nigeria.
West Afr J Med. 2004 Jul-Sep;23(3):194-7. doi: 10.4314/wajm.v23i3.28119.
Strongyloidiasis is one of the major human intestinal infections caused by a minute nematode, Strongyloides stercoralis. It is a soil-transmitted nematode of worldwide distribution, which resides in the small intestines of humans and is acquired by tissue penetration by the infective stage, filariform larva, of the worm. In the immunocompetent hosts, Strongyloides stercoralis infects only the mucosal of the small intestines and persists as an asymptomatic often chronic infection. In contrast, in the presence of immune suppression it has ability to multiply within the human host, known as hyperinfection. Its occurrence has been reported more commonly among adults.
AIM/OBJECTIVE: This study was undertaken to find the occurrence of Strongyloides stercoralis among children 0-5years who presented with diarrhea and then relate it to their nutritional status.
Following ethical approval, two hundred and twenty seven children, 118 boys and 109 girls, with complaints of diarrhoea, were randomly selected. A structured questionnaire was completed for each child. Anthropometric measurement was taken. Clinical assessment/diagnosis by the attending physician was also recorded. Stool specimen was collected and examined by wet preparation and formol-ether concentration methods. Infected children were treated.
Twelve (5.3 %) of all the children with diarrhoea were found to have Strongyloides stercoralis. All the infected children were malnourished while none of the normal nourished children had Strongyloides stercoralis (p=0.001).
Strongyloidiasis is a possible complication of Malnutrition in children who presented with diarrhoea.
粪类圆线虫病是由微小线虫粪类圆线虫引起的主要人类肠道感染之一。它是一种全球分布的土壤传播线虫,寄生于人类小肠,通过感染性丝状幼虫穿透组织而感染。在免疫功能正常的宿主中,粪类圆线虫仅感染小肠黏膜,并以无症状的慢性感染形式持续存在。相比之下,在免疫抑制的情况下,它能够在人类宿主体内繁殖,即所谓的高度感染。其发病在成年人中更为常见。
本研究旨在调查0至5岁腹泻儿童中粪类圆线虫的感染情况,并将其与营养状况相关联。
在获得伦理批准后,随机选取227名有腹泻症状的儿童,其中118名男孩,109名女孩。为每个儿童填写一份结构化问卷。进行人体测量。记录主治医生的临床评估/诊断结果。采集粪便样本,采用湿片法和甲醛-乙醚浓缩法进行检查。对感染儿童进行治疗。
在所有腹泻儿童中,12名(5.3%)被发现感染粪类圆线虫。所有感染儿童均营养不良,而营养正常的儿童均未感染粪类圆线虫(p = 0.001)。
粪类圆线虫病可能是腹泻儿童营养不良的并发症。