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[一名白塞病患者的粪类圆线虫超感染综合征]

[Strongyloides stercoralis hyperinfection syndrome in a patient with Behçet's Disease].

作者信息

Yılmaz Insu, Cağlar Banu, Akay Bengü Nisa, Alkız Gamze, Boyvat Ayşe, Akyol Aynur

机构信息

Erciyes Üniversitesi Tıp Fakültesi, Göğüs Hastalıkları Anabilim Dalı, Kayseri, Turkey.

出版信息

Turkiye Parazitol Derg. 2013;37(2):139-42. doi: 10.5152/tpd.2013.30.

Abstract

Strongyloides stercoralis is endemic in the tropical and subtropical areas of the world. It is a soil-transmitted intestinal nematode affecting anywhere from 30 to 100 million people worldwide. Strongyloides stercoralis is capable of causing autoinfection, which increases larval migration and proliferation in the host. This condition may lead to hyperinfection syndrome which has the potential to cause serious life threatening complications, especially in immunosuppressed patients. Thus, Strongyloides stercoralis hyperinfection syndrome should be suspected if there are clinical clues including gastrointestinal tract symptoms (abdominal pain, nausea, vomiting, diarrhoea), respiratory tract symptoms (cough, dyspnoea, wheezing, haemoptysis), skin symptoms (pruritus, erythema) and peripheral eosinophilia in a patient with underlying risk factors. Herein, we report a case of Strongyloides stercoralis hyperinfection syndrome in a patient with Behçet's Disease on immunosuppressive treatment.

摘要

粪类圆线虫在世界热带和亚热带地区呈地方性流行。它是一种经土壤传播的肠道线虫,全球约有3000万至1亿人受其影响。粪类圆线虫能够引起自身感染,从而增加宿主体内幼虫的移行和增殖。这种情况可能导致超感染综合征,有可能引发严重的危及生命的并发症,尤其是在免疫抑制患者中。因此,如果有潜在危险因素的患者出现包括胃肠道症状(腹痛、恶心、呕吐、腹泻)、呼吸道症状(咳嗽、呼吸困难、喘息、咯血)、皮肤症状(瘙痒、红斑)和外周血嗜酸性粒细胞增多等临床线索,应怀疑粪类圆线虫超感染综合征。在此,我们报告一例正在接受免疫抑制治疗的白塞病患者发生粪类圆线虫超感染综合征的病例。

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