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[子宫肌瘤。栓塞术:最新技术]

[Uterine fibroids. Embolization: state-of-the-art].

作者信息

Le Dref O, Pelage J-P, Jacob D

机构信息

Service de radiologie viscérale et vasculaire, hôpital Lariboisière, 2, rue Ambroise Paré, 75475 Paris cedex 10, France.

出版信息

Gynecol Obstet Fertil. 2004 Dec;32(12):1057-63. doi: 10.1016/j.gyobfe.2004.08.021.

Abstract

Uterine artery embolization is a radiological procedure consisting in occluding the perifibroid arterial plexus to induce fibroid ischemia. To date, with more than 50,000 women treated worldwide, embolization seems to be a valuable alternative to hysterectomy and multiple myomectomies particularly in women with severe menorrhagia. Embolization should ideally be performed in case of intramural or submucosal uterine fibroids. It must be preferrably realized in case of multiple fibroids, be they intramural or submucosal (when hysteroscopic resection is not feasible). Complication rates are low if large calibrated microspheres are used to perform embolization and if pedunculated subserosal fibroids are excluded. In case of associated adenomyosis clinical recurrence seems more frequent. The role of embolization as an alternative to a single myomectomy, particularly in young women desiring future pregnancy remains a matter of debate and should be evaluated with clinical randomized trials. Pluridisciplinary management of women is the key to a widespread acceptance of uterine artery embolization in the management of uterine fibroids.

摘要

子宫动脉栓塞术是一种放射学操作,其在于闭塞肌瘤周围动脉丛以诱导肌瘤缺血。迄今为止,全球已有超过50000名女性接受了治疗,栓塞术似乎是子宫切除术和多次肌瘤切除术的一种有价值的替代方法,尤其是对于有严重月经过多的女性。理想情况下,栓塞术应在壁间或黏膜下子宫肌瘤的情况下进行。如果是多发性肌瘤,无论其为壁间还是黏膜下肌瘤(宫腔镜切除术不可行时),最好进行栓塞术。如果使用大尺寸校准微球进行栓塞术且排除有蒂的浆膜下肌瘤,并发症发生率较低。在合并子宫腺肌病的情况下,临床复发似乎更常见。栓塞术作为单次肌瘤切除术的替代方法的作用,尤其是对于希望未来怀孕的年轻女性,仍存在争议,应通过临床随机试验进行评估。对女性进行多学科管理是子宫动脉栓塞术在子宫肌瘤管理中被广泛接受的关键。

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