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惊厥性和非惊厥性癫痫持续状态的脑电图

EEG in convulsive and nonconvulsive status epilepticus.

作者信息

Brenner Richard P

机构信息

Departments of Neurology and Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA 15213, U.S.A.

出版信息

J Clin Neurophysiol. 2004 Sep-Oct;21(5):319-31.

Abstract

Seizures and status epilepticus (SE) are serious complications in intensive care unit (ICU) patients. SE is often divided into convulsive and nonconvulsive types, based on clinical features. The EEG is helpful in further dividing SE into those that are generalized from onset, or have a partial onset, because this may be difficult to do clinically. This is particularly true in patients with tonic-clonic seizures, which may be generalized from onset, or secondarily generalized. Rarely in the ICU, although not infrequently in epilepsy monitoring units, the EEG may indicate that the event is nonepileptic, such as pseudostatus epilepticus. Nonconvulsive SE is often difficult to diagnose, be it partial or generalized, and the diagnosis is usually delayed. Furthermore, although an EEG is required to verify the diagnosis, there are not widely accepted criteria to diagnose this entity, particularly in obtunded/comatose patients. For example, it is controversial whether several EEG patterns, such as periodic lateralized and generalized periodic epileptiforms, are ictal or interictal. This article reviews EEG findings in different types of SE in adults and provides numerous examples.

摘要

癫痫发作和癫痫持续状态(SE)是重症监护病房(ICU)患者的严重并发症。根据临床特征,SE通常分为惊厥性和非惊厥性类型。脑电图有助于进一步将SE分为起病即全身性发作或部分性发作的类型,因为临床上可能难以做到这一点。对于强直阵挛性发作的患者尤其如此,这类发作可能起病即全身性发作,也可能是继发性全身性发作。在ICU中这种情况很少见,不过在癫痫监测病房并不罕见,脑电图可能显示该事件为非癫痫性,比如假性癫痫持续状态。非惊厥性SE通常难以诊断,无论是部分性还是全身性发作,而且诊断通常会延迟。此外,虽然需要脑电图来证实诊断,但对于诊断这一病症并没有广泛认可的标准,尤其是在意识模糊/昏迷的患者中。例如,几种脑电图模式,如周期性一侧性癫痫样放电和全身性周期性癫痫样放电,究竟是发作期还是发作间期的表现,存在争议。本文回顾了成人不同类型SE的脑电图表现,并提供了大量实例。

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