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癫痫发作后长时间昏迷:非惊厥性癫痫持续状态、药物作用还是癫痫发作后状态?

Prolonged postictal stupor: nonconvulsive status epilepticus, medication effect, or postictal state?

作者信息

Langheinrich Tobias Christoph, Chattopadhyay Arup, Kuc Sue, Reuber Markus

机构信息

Neurology, Sheffield Teaching Hospital NHS Trust, Glossop Road, Sheffield, South Yorkshire S10 2JF, UK.

出版信息

Epilepsy Behav. 2005 Nov;7(3):548-51. doi: 10.1016/j.yebeh.2005.06.018. Epub 2005 Sep 27.

Abstract

We describe a patient who entered a stuporous state after receiving benzodiazepine treatment for generalized tonic-clonic status epilepticus. A diagnosis of generalized NCSE with tonic seizures was made on the basis of the clinical picture and response to barbiturate anaesthetic, although the EEG pattern was not typical of the changes previously described in tonic seizures-tonic status epilepticus. This report discusses the differential diagnosis of postictal stupor, nonconvulsive status epilepticus with tonic seizures and sedation caused by the emergency treatment of status epilepticus, and summarizes the literature on tonic seizures and tonic status epilepticus.

摘要

我们描述了一名患者,其在接受苯二氮䓬类药物治疗全身性强直阵挛性癫痫持续状态后进入昏迷状态。尽管脑电图模式并非先前描述的强直发作 - 强直癫痫持续状态的典型变化,但根据临床表现和对巴比妥类麻醉剂的反应,诊断为伴有强直发作的全身性非惊厥性癫痫持续状态。本报告讨论了癫痫发作后昏迷、伴有强直发作的非惊厥性癫痫持续状态以及癫痫持续状态急诊治疗引起的镇静的鉴别诊断,并总结了有关强直发作和强直癫痫持续状态的文献。

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