Chawla Ashis, Bowles Ben, Zini Armand
Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
Urology. 2004 Dec;64(6):1212-5. doi: 10.1016/j.urology.2004.07.007.
To examine patient compliance, complications, and significance of rare nonmotile sperm (RNMS) after no-scalpel vasectomy.
We reviewed the records of 690 consecutive men who had undergone vasectomy at our institution between 1996 and 2002. All men were instructed to submit two initial semen samples for analysis (3 and 4 months after vasectomy) and additional samples (at 2-month intervals) if sperm were identified on the initial and subsequent analyses. All patient complaints (telephone and clinic visit) were recorded.
A total of 315 men (45.6%) did not submit any semen samples. Of the 295 men who submitted two samples, 176 (60%) were azoospermic, 110 (37%) had RNMS, and 9 men (3%) had rare motile sperm (the vasectomy of 1 of these 9 men subsequently failed). Of the 110 men with RNMS, 83 submitted one or more additional semen samples. Of these 83 men, 62 (75%) had become azoospermic, 20 (24%) had persistent RNMS, and 1 (1%) subsequently had a failed vasectomy (with motile sperm). The 2 patients with failure underwent a repeat vasectomy (failure rate 0.67% [2 of 295]). A total of 69 patients (10%) reported a complaint, but only 9 (1.5%) of these men returned for clinical examination. No surgical complications and no pregnancies occurred.
Our data show that despite aggressive counseling, compliance with follow-up testing is very poor. Patient-reported complaints are common but minor. We found that most men with RNMS become azoospermic and propose that the presence of RNMS is consistent with a successful vasectomy. However, long-term, prospective studies are needed to assess the risk of late failure in men with RNMS.
研究无刀输精管结扎术后患者的依从性、并发症以及罕见的非活动精子(RNMS)的意义。
我们回顾了1996年至2002年间在我院接受输精管结扎术的690例连续男性患者的记录。所有男性均被要求提交两份初始精液样本进行分析(输精管结扎术后3个月和4个月),如果在初始及后续分析中发现精子,则需提交额外样本(每隔2个月)。记录所有患者的投诉(电话及门诊就诊)。
共有315名男性(45.6%)未提交任何精液样本。在提交两份样本的295名男性中,176名(60%)无精子,110名(37%)有RNMS,9名男性(3%)有罕见的活动精子(这9名男性中的1名输精管结扎术随后失败)。在110名有RNMS的男性中,83名提交了一份或多份额外的精液样本。在这83名男性中,62名(75%)变为无精子,20名(24%)持续有RNMS,1名(1%)随后输精管结扎术失败(有活动精子)。2例失败患者接受了重复输精管结扎术(失败率0.67%[295例中的2例])。共有69名患者(10%)报告有投诉,但其中只有9名(1.5%)男性返回进行临床检查。未发生手术并发症及妊娠。
我们的数据表明,尽管进行了积极的咨询,但随访检测的依从性非常差。患者报告的投诉很常见但不严重。我们发现大多数有RNMS的男性会变为无精子,并提出RNMS的存在与成功的输精管结扎术一致。然而,需要长期的前瞻性研究来评估有RNMS男性后期失败的风险。