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输精管切除术后持续性精子症:英国泌尿外科医生的一项调查

Persistent spermatozoa after vasectomy: a survey of British urologists.

作者信息

Benger J R, Swami S K, Gingell J C

机构信息

Bristol Urological Institute, Southmead Hospital, Westbury-On-Trym, UK.

出版信息

Br J Urol. 1995 Sep;76(3):376-9.

PMID:7551851
Abstract

OBJECTIVES

To determine the rate of, and main indications for, repeat vasectomy in our department, and to assist in policy-making procedures by determining how urologists in England and Wales manage those men who show small but persistent quantities of motile or non-motile spermatozoa in their ejaculate after vasectomy.

SUBJECTS AND METHODS

A retrospective review of all of the vasectomies and repeat vasectomies performed by the Urology Department at Southmead Hospital during a 14-month period was undertaken to determine the rate of and indications for repeat vasectomy. Subsequently, every consultant urologist in England and Wales was canvassed with a questionnaire to determine whether they repeated vasectomy in the presence of persistent motile or non-motile sperms and if so, after what time interval. Any experience of pregnancies arising from these groups was also assessed, and any relevant comments invited.

RESULTS

The local review revealed that 5% of all vasectomies were repeated within 6-36 months. Of these, 87% were performed because of persistent sperms in post-vasectomy semen samples, the majority of which showed sperm concentrations of one in 50 to one in 100 high-power fields. A response of 56% was obtained to the questionnaire and of those responding, 23% never repeated a vasectomy where there were presistent non-motile sperms, but almost all urologists would eventually repeat vasectomy where motile sperms were present. The median interval between the first and second vasectomies was 6 months and 12 months for motile and non-motile sperm, respectively. Apart from those cases already published, there was little experience of pregnancy arising from men with persistently few motile or non-motile sperms.

CONCLUSIONS

The risk of pregnancy occurring in the presence of non-motile sperms was estimated to be less than the established risk of late recanalization, and this survey provides both logical and medico-legal support for issuing a 'special clearance' to men with few persistent non-motile sperm after vasectomy, providing the risks of pregnancy are properly discussed and documented. For motile sperm, however, there appears to be a stronger precedent for repeating the vasectomy. The technique used for post-vasectomy semen analysis was also an important consideration when determining any policy regarding such cases.

摘要

目的

确定我院重复输精管切除术的发生率及主要指征,并通过了解英格兰和威尔士的泌尿科医生如何处理输精管切除术后射精中出现少量但持续存在的活动或不活动精子的男性患者,协助制定决策程序。

对象与方法

对南米德医院泌尿科在14个月期间进行的所有输精管切除术和重复输精管切除术进行回顾性研究,以确定重复输精管切除术的发生率和指征。随后,向英格兰和威尔士的每位泌尿科顾问医生发放问卷,以确定他们在存在持续活动或不活动精子的情况下是否会重复输精管切除术,以及如果会,在多长时间间隔后进行。还评估了这些人群中怀孕的任何情况,并邀请提供任何相关意见。

结果

本地回顾显示,所有输精管切除术中5%在6至36个月内进行了重复手术。其中,87%是因为输精管切除术后精液样本中存在持续精子而进行的,其中大多数精子浓度为每50至100个高倍视野中有1个。问卷回复率为56%,在回复者中,23%在存在持续不活动精子时从未重复输精管切除术,但几乎所有泌尿科医生最终都会在存在活动精子时重复输精管切除术。第一次和第二次输精管切除术之间的中位间隔时间,活动精子情况为6个月,不活动精子情况为12个月。除了已发表的病例外,精子持续少量活动或不活动的男性怀孕情况鲜有报道。

结论

估计存在不活动精子时怀孕的风险低于既定的晚期再通风险,并且这项调查为在适当讨论并记录怀孕风险后,向输精管切除术后有少量持续不活动精子的男性发放“特别许可”提供了逻辑和医学法律支持。然而,对于活动精子,重复输精管切除术似乎有更强的先例。在确定此类病例的任何政策时,输精管切除术后精液分析所采用的技术也是一个重要的考虑因素。

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