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肥胖症患者与非肥胖患者腹腔镜根治性肾手术的比较。

Comparison of laparoscopic radical renal surgery in morbidly obese and non-obese patients.

作者信息

Kapoor Anil, Nassir Anmar, Chew Ben, Gillis Aubrey, Luke Patrick, Whelan Paul

机构信息

Section of Urology, Department of Surgery, McMaster University, Hamilton, Ontario.

出版信息

J Endourol. 2004 Sep;18(7):657-60. doi: 10.1089/end.2004.18.657.

Abstract

BACKGROUND AND PURPOSE

Laparoscopic radical nephrectomy is rapidly becoming accepted as the preferred management of low-stage renal masses not amenable to partial nephrectomy. Minimally invasive surgery is advantageous to decrease perioperative and postoperative morbidity and allows patients to return to normal activities faster. Obesity has been a relative contraindication to this technique, and these patients have traditionally undergone open surgery. We present a review of 23 morbidly obese patients in comparison with patients who were not morbidly obese who underwent radical laparoscopic nephrectomy and nephroureterectomy at our institution.

PATIENTS AND METHODS

Hospital charts between April 2001 and October 2003 were reviewed for morbidly obese patients undergoing transperitoneal laparoscopic renal surgery who were compared with age- and sex-matched control patients who underwent laparoscopic renal surgery in the same institution for similar indications. The data were collected at the time of the surgery.

RESULTS

Twenty-three patients with a mean BMI of 42.2 kg/m2 underwent successful transperitoneal laparoscopic surgery. The mean specimen mass was 865 g, which was significantly larger than in the control group. The mean operative time was 200 minutes, which was around half an hour longer than in the matched group. The mean estimated blood loss was 243 mL, which was comparable to that of the controls. There were two perioperative complications, and the mean hospital stay was 4.5 days, 1 day longer than in the control group.

CONCLUSIONS

Laparoscopic transperitoneal renal surgery is technically more difficult in morbidly obese patients but is a feasible, effective, minimally invasive method of removing renal malignancies. It offers decreased respiratory and cardiac morbidity in this higher-risk population. This study showed a complication profile similar to that in non-obese patients.

摘要

背景与目的

腹腔镜根治性肾切除术正迅速成为无法进行部分肾切除术的低分期肾肿块的首选治疗方法。微创手术有利于降低围手术期和术后发病率,并使患者能更快恢复正常活动。肥胖一直是这项技术的相对禁忌证,这类患者传统上接受开放手术。我们对23例病态肥胖患者与我院接受腹腔镜根治性肾切除术和肾输尿管切除术的非病态肥胖患者进行了比较并进行综述。

患者与方法

回顾2001年4月至2003年10月期间接受经腹腹腔镜肾脏手术的病态肥胖患者的医院病历,并与同一机构因类似适应证接受腹腔镜肾脏手术的年龄和性别匹配的对照患者进行比较。数据在手术时收集。

结果

23例平均体重指数(BMI)为42.2kg/m²的患者成功接受了经腹腹腔镜手术。平均标本重量为865g,显著大于对照组。平均手术时间为200分钟,比匹配组约长半小时。平均估计失血量为243mL,与对照组相当。有2例围手术期并发症,平均住院时间为4.5天,比对照组长1天。

结论

腹腔镜经腹肾脏手术在病态肥胖患者中技术上更具挑战性,但仍是一种可行、有效的微创切除肾脏恶性肿瘤的方法。它在这一高风险人群中降低了呼吸和心脏发病率。本研究显示并发症情况与非肥胖患者相似。

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