Fazeli-Matin S, Gill I S, Hsu T H, Sung G T, Novick A C
Department of Urology, Minimally Invasive Surgery Center, Cleveland Clinic Foundation, Ohio 44195, USA.
J Urol. 1999 Sep;162(3 Pt 1):665-9. doi: 10.1097/00005392-199909010-00005.
The efficacy and morbidity of laparoscopic renal and adrenal surgery in comparison to open surgery in obese patients are unknown. This retrospective study was performed to compare the outcome of laparoscopic versus open renal and adrenal surgery in the markedly and morbidly obese patient (body mass index 30 or greater).
The study group comprised all obese patients undergoing laparoscopic renal and adrenal surgery (laparoscopic group) from August 1997 to February 1998 at our institution. The majority of procedures were performed using a retroperitoneoscopic approach via the flank. These patients were compared with all obese patients undergoing open renal and adrenal surgery (open group) from 1994 to 1998. Open group patients with factors precluding laparoscopic surgery were excluded from the study (mass greater than 10 cm., renal vein and/or inferior vena caval thrombus and extension outside Gerota's fascia).
There were 21 obese patients in each group and baseline parameters were comparable between groups. Median body mass index in the laparoscopic and open groups was 34 and 31, respectively. Median surgical time between the laparoscopic (210 minutes) and open (185) groups was comparable (p = 0.16). However, the laparoscopic group had decreased blood loss (100 versus 350 ml., p<0.001), quicker resumption of oral intake and ambulation (less than 1 versus 5 days, p<0.001), decreased narcotic analgesic requirements (12 versus 279 mg., p<0.001), shorter median hospital stay (less than 1 versus 5 days, p<0.001) and quicker convalescence (3 versus 9 weeks, p<0.001). There were 6 complications in 4 laparoscopic cases and 14 in 9 open surgery cases (p = 0.16).
Markedly obese patients have an increased risk of complications from surgery, regardless of the approach. Our data suggest that laparoscopic renal and adrenal surgery is technically feasible in the markedly and morbidly obese patient, and compared with open surgery results in significantly decreased blood loss, quicker return of bowel function, less analgesic requirement, shorter convalescence and reduced hospital stay.
与开放手术相比,肥胖患者行腹腔镜肾和肾上腺手术的疗效及发病率尚不清楚。本回顾性研究旨在比较显著肥胖和病态肥胖患者(体重指数30或更高)行腹腔镜与开放肾和肾上腺手术的结果。
研究组包括1997年8月至1998年2月在我院接受腹腔镜肾和肾上腺手术的所有肥胖患者(腹腔镜组)。大多数手术采用经侧腹后腹腔镜入路。将这些患者与1994年至1998年接受开放肾和肾上腺手术的所有肥胖患者(开放组)进行比较。排除有腹腔镜手术禁忌因素的开放组患者(肿块大于10 cm、肾静脉和/或下腔静脉血栓以及超出肾周筋膜范围)。
每组有21例肥胖患者,两组间基线参数具有可比性。腹腔镜组和开放组的中位体重指数分别为34和31。腹腔镜组(210分钟)和开放组(185分钟)的中位手术时间具有可比性(p = 0.16)。然而,腹腔镜组的失血量减少(100对350 ml,p<0.001),口服摄入和下床活动恢复更快(不到1天对5天,p<0.001),对麻醉性镇痛药的需求减少(12对279 mg,p<0.001),中位住院时间缩短(不到1天对5天,p<0.001),康复更快(3周对9周,p<0.001)。4例腹腔镜手术患者中有6例出现并发症,9例开放手术患者中有14例出现并发症(p = 0.16)。
无论采用何种手术方式,显著肥胖患者手术并发症风险均增加。我们的数据表明,腹腔镜肾和肾上腺手术在显著肥胖和病态肥胖患者中技术上可行,与开放手术相比,失血量显著减少,肠功能恢复更快,镇痛需求更少,康复期更短,住院时间缩短。