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单卵双胞胎中的III型自身免疫性多腺体综合征:一例报告

Autoimmune polyglandular syndrome type III in monozygotic twins: a case report.

作者信息

Ugur-Altun B, Arikan E, Guldiken S, Kara M, Tugrul A

机构信息

Division of Endocrinology and Metabolism, Faculty of Medicine, University of Trakya, Edirne, Turkey.

出版信息

Acta Clin Belg. 2004 Jul-Aug;59(4):225-8.

Abstract

Autoimmune polyglandular syndrome is characterized by the coexistence of several autoimmune diseases, affecting predominantly the endocrine glands. Autoimmune polyglandular syndrome type III, as a subdivision of autoimmune polyglandular syndrome type II, is the co-occurrence of autoimmune thyroid disease with other autoimmune disorders without Addison disease. We present a rare case of autoimmune polyglandular syndrome type III in monozygotic twins. One of the twins also had autoimmune leukopenia. To our knowledge, leukopenia is the first mentioned coexistence in the literature of autoimmune polyglandular syndrome.

摘要

自身免疫性多腺体综合征的特征是几种自身免疫性疾病同时存在,主要影响内分泌腺。自身免疫性多腺体综合征III型作为自身免疫性多腺体综合征II型的一个细分,是自身免疫性甲状腺疾病与其他自身免疫性疾病同时出现且无艾迪生病。我们报告了一例单卵双胞胎患自身免疫性多腺体综合征III型的罕见病例。其中一名双胞胎还患有自身免疫性白细胞减少症。据我们所知,白细胞减少症是自身免疫性多腺体综合征文献中首次提及的共存病症。

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