Dragan Laryssa R, Aghaian Elsa, Vora Robin, Kim Grace E, Seiff Stuart R
Department of Ophthalmology, University of California, San Francisco, California 94131-0344, USA.
Ophthalmic Plast Reconstr Surg. 2004 Nov;20(6):469-71. doi: 10.1097/01.iop.0000144787.69694.94.
A yolk sac tumor, also known as an endodermal sinus tumor, was diagnosed in a 15-month-old infant who presented with rapidly progressive right eye proptosis. Imaging of the orbits and brain revealed a mass in the right orbit, middle cranial fossa, and pterygopalatine fossa. A lateral orbitotomy was performed to take a biopsy specimen and to partially debulk the tumor secondary to signs of optic nerve compromise. The biopsy specimen revealed a yolk sac tumor, and the patient underwent systemic chemotherapeutic treatment. Because orbital endodermal sinus tumors have been infrequently reported, there are no firm prognostic or treatment guidelines. Our case demonstrates that early recognition, limited orbital debulking, and chemotherapy can have an excellent short-term outcome.
一名15个月大的婴儿被诊断出患有卵黄囊瘤，也称为内胚窦瘤，该婴儿出现右眼迅速进行性突出。眼眶和脑部成像显示右眼眶、中颅窝和翼腭窝有肿块。进行了外侧眼眶切开术以获取活检标本，并因视神经受压迹象对肿瘤进行部分减瘤。活检标本显示为卵黄囊瘤，患者接受了全身化疗。由于眼眶内胚窦瘤的报道较少，因此没有确定的预后或治疗指南。我们的病例表明，早期识别、有限的眼眶减瘤和化疗可取得优异的短期疗效。
