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缝合材料:它们会影响皮瓣尿道成形术中的瘘管和狭窄发生率吗?

Suture materials: do they affect fistula and stricture rates in flap urethroplasties?

作者信息

Cimador M, Castagnetti M, Milazzo M, Sergio M, De Grazia E

机构信息

Paediatric Surgery Unit, Istituto Materno Infantile, University of Palermo, Palermo, Italy.

出版信息

Urol Int. 2004;73(4):320-4. doi: 10.1159/000081592.

Abstract

INTRODUCTION

The effect of suture materials on urethroplasty complications is debated. Indeed, materials with a delayed absorption might either reduce the incidence of fistulas by ensuring a prolonged approximation of neo-urethral edges or increase the risk of urethral strictures due to a prolonged tissue reaction during suture absorption. We retrospectively evaluated the role of suture materials in the complication rate of urethroplasty procedures performed in our institution over a 10-year period.

PATIENTS AND METHODS

Three hundred and thirty-six boys undergoing a flap procedure (parameatal based, preputial tube, or onlay preputial flap) for hypospadias repair were considered for this study. The patients were stratified into two groups according to the suture material used for urethroplasty. Polyglactin (Vicryl), a polyfilament with intermediate absorption, was used in 254 group A patients, whereas polydioxanone (PDS), a monofilament with prolonged absorption, was used in 82 group B patients. The success of a one-stage repair and stricture and fistula rates were evaluated.

RESULTS

A successful one-stage repair was achieved in 82% of the group A and in 83% of the group B patients (p = 0.97). No statistically significant differences were noted in fistula and/or stricture rates in the two groups, even considering each procedure separately.

CONCLUSIONS

This series suggests that suture materials do not affect the complication rate in flap urethroplasty procedures. Appropriate technique, meticulous surgery, and surgeon experience seem to be more crucial factors. A randomized trial is warranted.

摘要

引言

缝线材料对尿道成形术并发症的影响存在争议。实际上,吸收延迟的材料可能通过确保新尿道边缘的长时间贴合来降低瘘管发生率,也可能因缝线吸收过程中组织反应延长而增加尿道狭窄的风险。我们回顾性评估了缝线材料在我们机构10年间进行的尿道成形术并发症发生率中的作用。

患者与方法

本研究纳入了336例接受皮瓣手术(尿道口基底皮瓣、包皮管或覆盖包皮瓣)修复尿道下裂的男孩。根据尿道成形术所用的缝线材料,将患者分为两组。A组254例患者使用聚乙醇酸(薇乔),这是一种吸收中期的多丝缝线,而B组82例患者使用聚二氧六环酮(PDS),这是一种吸收期延长的单丝缝线。评估一期修复的成功率以及狭窄和瘘管发生率。

结果

A组82%的患者和B组83%的患者实现了成功的一期修复(p = 0.97)。两组在瘘管和/或狭窄发生率方面未发现统计学上的显著差异,即使分别考虑每种手术也是如此。

结论

本系列研究表明,缝线材料不影响皮瓣尿道成形术的并发症发生率。适当的技术、细致的手术操作和外科医生的经验似乎是更关键的因素。有必要进行一项随机试验。

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