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小儿患者的尿道下裂失败案例。

Failed hypospadias in paediatric patients.

机构信息

Section of Paediatric Urology and Paediatric Surgery Unit, Department for Mother and Child Care and Urology, University of Palermo, Via A. Giordano 3, 90127 Palermo, Italy.

出版信息

Nat Rev Urol. 2013 Nov;10(11):657-66. doi: 10.1038/nrurol.2013.164. Epub 2013 Aug 6.

Abstract

Failed hypospadias refers to any hypospadias repair that leads to complications or causes patient dissatisfaction. The complication rate after hypospadias repairs ranges from 5-70%, but the actual incidence of failed hypospadias is unknown as complications can become apparent many years after surgery and series with lifelong follow-up data do not exist. Moreover, little is known about uncomplicated repairs that fail in terms of patient satisfaction. Risk factors for complications include factors related to the hypospadias (severity of the condition and characteristics of the urethral plate), the patient (age at surgery, endocrine environment, and wound healing impairment), the surgeon (technique selection and surgeon expertise), and the procedure (technical details and postoperative management). The most important factors for preventing complications are surgeon expertise (number of cases treated per year), interposition of a barrier layer between the urethroplasty and the skin, and postoperative urinary drainage. Major complications associated with failed hypospadias include residual curvature, healing complications (preputial dehiscence, glans dehiscence, fistula formation, and urethral breakdown), urethral obstruction (meatal stenosis, urethral stricture, and functional obstruction), urethral diverticula, hairy urethra, and penile skin deficiency.

摘要

失败的尿道下裂是指任何导致并发症或患者不满意的尿道下裂修复。尿道下裂修复后的并发症发生率为 5-70%,但由于手术后多年才会出现并发症,而且没有长期随访数据的系列报道,因此实际的失败尿道下裂发生率尚不清楚。此外,对于复杂修复后出现的患者不满意的情况,我们知之甚少。并发症的危险因素包括与尿道下裂相关的因素(病情严重程度和尿道板特征)、患者相关因素(手术年龄、内分泌环境和伤口愈合受损)、外科医生相关因素(技术选择和外科医生专业知识)以及手术相关因素(技术细节和术后管理)。预防并发症的最重要因素是外科医生的专业知识(每年治疗的病例数)、尿道成形术与皮肤之间的隔离层、以及术后尿液引流。与失败的尿道下裂相关的主要并发症包括残余弯曲、愈合并发症(包皮裂开、龟头裂开、瘘管形成和尿道破裂)、尿道梗阻(尿道口狭窄、尿道狭窄和功能性梗阻)、尿道憩室、多毛尿道和阴茎皮肤缺乏。

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