[从卷柏中分离鉴定一种新的木脂苷]

[The isolation and identification of a new lignanoside from Selaginella tamariscina (Beauv.) Spring].

作者信息

Zheng Xiao-ke, Shi She-po, Bi Yue-feng, Feng Wei-sheng, Wang Ji-feng, Niu Jian-zhao

机构信息

Henan College of Traditional Chinese Medicine, Zhengzhou 450008, China.

出版信息

Yao Xue Xue Bao. 2004 Sep;39(9):719-21.

PMID:15606021

Abstract

AIM

To study the chemical constituents of Selaginella tamariscina (Beauv.) Spring.

METHODS

The compounds were isolated and purified by macroporous adsorption resin, Sephadex LH-20 and silica gel column chromatography and identified on the basis of their physicochemical and spectral data.

RESULTS

Four compounds were obtained from the n-BuOH fraction of 70% acetone extracts. Their structures were elucidated as (7S, 8R)-7, 8-dihydro-7-(4-hydroxy-3,5-dimethoxyphenyl)-8-hydroxymethyl-[1'-( 7'-hydroxyethyl)-5' methoxyl] benzofuran-4-O-beta-D-glucopyranoside (tamariscinoside C, I), D-mannitol (II), tyrosine (II), shikimic acid (IV).

CONCLUSION

Compound I is a new compound, compounds II and III were obtained from the genius for the first time, compound IV was yielded from the plant for the first time.

摘要

目的

研究卷柏的化学成分。

方法

采用大孔吸附树脂、葡聚糖凝胶LH - 20及硅胶柱色谱法对化合物进行分离纯化，并根据其理化性质和光谱数据进行鉴定。

结果

从70%丙酮提取物的正丁醇部位得到4个化合物。其结构经鉴定分别为(7S, 8R)-7, 8 - 二氢 - 7 - (4 - 羟基 - 3,5 - 二甲氧基苯基)-8 - 羟甲基 - [1'-(7'-羟乙基)-5' - 甲氧基]苯并呋喃 - 4 - O - β - D - 吡喃葡萄糖苷（卷柏苷C，I）、D - 甘露醇（II）、酪氨酸（III）、莽草酸（IV）。