Suppr超能文献

在门诊就诊时进行简短的动机干预可减少可卡因和海洛因的使用。

Brief motivational intervention at a clinic visit reduces cocaine and heroin use.

作者信息

Bernstein Judith, Bernstein Edward, Tassiopoulos Katherine, Heeren Timothy, Levenson Suzette, Hingson Ralph

机构信息

Department of Emergency Medicine, Boston University School of Medicine, 818 Harrison St. (Dowling 1), Boston, MA 02118, USA.

出版信息

Drug Alcohol Depend. 2005 Jan 7;77(1):49-59. doi: 10.1016/j.drugalcdep.2004.07.006.

Abstract

BACKGROUND

Brief intervention is effective for alcohol misuse, but not adequately tested in the clinical setting with drug using patients. This study tested the impact of a single, structured encounter targeting cessation of drug use, conducted between peer educators and out-of-treatment cocaine and heroin users screened in the context of a routine medical visit.

METHODS

A randomized, controlled trial was conducted in inner-city teaching hospital outpatient clinics with 3 and 6 months follow-up by blinded observers. Drug abstinence was documented by RIA hair testing. Analysis was limited to enrollees with drug-positive hair at baseline.

RESULTS

Among 23,669 patients screened 5/98-11/00, 1232 (5%) were eligible, and 1175 enrolled. Enrollees (mean age 38 years) were 29% female, 62% non-hispanic black, 23% hispanic, 46% homeless. Among those with positive hair at entry, the follow-up rate was 82%. The intervention group was more likely to be abstinent than the control group for cocaine alone (22.3% versus 16.9%), heroin alone (40.2% versus 30.6%), and both drugs (17.4% versus 12.8%), with adjusted OR of 1.51-1.57. Cocaine levels in hair were reduced by 29% for the intervention group and only 4% for the control group. Reductions in opiate levels were similar (29% versus 25%).

CONCLUSIONS

Brief motivational intervention may help patients achieve abstinence from heroin and cocaine.

摘要

背景

简短干预对酒精滥用有效,但在药物使用患者的临床环境中尚未得到充分测试。本研究测试了在常规医疗就诊背景下,同伴教育者与未接受治疗的可卡因和海洛因使用者之间进行的单次结构化干预对戒毒的影响。

方法

在市中心教学医院门诊进行了一项随机对照试验,由盲法观察者进行3个月和6个月的随访。通过放射免疫分析毛发检测记录药物戒断情况。分析仅限于基线时毛发药物检测呈阳性的参与者。

结果

在1998年5月至2000年11月筛查的23669名患者中,1232名(5%)符合条件,1175名登记入组。登记入组者(平均年龄38岁)中,女性占29%,非西班牙裔黑人占62%,西班牙裔占23%,无家可归者占46%。在入组时毛发检测呈阳性的患者中,随访率为82%。干预组单独使用可卡因(22.3%对16.9%)、单独使用海洛因(40.2%对30.6%)以及两种药物均戒断的可能性均高于对照组(17.4%对12.8%),调整后的比值比为1.51 - 1.57。干预组毛发中的可卡因水平降低了29%,而对照组仅降低了4%。阿片类药物水平的降低情况相似(29%对25%)。

结论

简短的动机性干预可能有助于患者戒除海洛因和可卡因。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验